ID   A0A1J1IZG8_9DIPT        Unreviewed;       897 AA.
AC   A0A1J1IZG8;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Exocyst complex component 2 {ECO:0000256|ARBA:ARBA00017526, ECO:0000256|RuleBase:RU365069};
GN   ORFNames=CLUMA_CG018700 {ECO:0000313|EMBL:CRL05667.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRL05667.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRL05667.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC       exocytic vesicles with fusion sites on the plasma membrane.
CC       {ECO:0000256|ARBA:ARBA00002660, ECO:0000256|RuleBase:RU365069}.
CC   -!- SUBUNIT: Component of the exocyst complex.
CC       {ECO:0000256|RuleBase:RU365069}.
CC   -!- SIMILARITY: Belongs to the SEC5 family. {ECO:0000256|ARBA:ARBA00010578,
CC       ECO:0000256|RuleBase:RU365069}.
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DR   EMBL; CVRI01000065; CRL05667.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1IZG8; -.
DR   STRING; 568069.A0A1J1IZG8; -.
DR   OrthoDB; 2901642at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0000145; C:exocyst; IEA:UniProtKB-UniRule.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048731; P:system development; IEA:UniProt.
DR   CDD; cd00603; IPT_PCSR; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR029175; EXOC2/Sec5.
DR   InterPro; IPR039481; EXOC2/Sec5_N_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   PANTHER; PTHR13043:SF1; EXOCYST COMPLEX COMPONENT 2; 1.
DR   PANTHER; PTHR13043; EXOCYST COMPLEX COMPONENT SEC5; 1.
DR   Pfam; PF15469; Sec5; 1.
DR   Pfam; PF01833; TIG; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
PE   3: Inferred from homology;
KW   Exocytosis {ECO:0000256|ARBA:ARBA00022483, ECO:0000256|RuleBase:RU365069};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|RuleBase:RU365069};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365069}.
FT   DOMAIN          5..86
FT                   /note="IPT/TIG"
FT                   /evidence="ECO:0000259|Pfam:PF01833"
FT   DOMAIN          126..892
FT                   /note="Exocyst complex component EXOC2/Sec5 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15469"
SQ   SEQUENCE   897 AA;  101663 MW;  689D8A937D345E57 CRC64;
     MAPPPLVTGI SPKEGPPGTK ITIRGENLGV KANDLIGVQI CGGDCSFEWQ SRNKIIARTG
     INGTKGKGDV IVTSLSGGAG TSTVQFRTYT EMIGPLKESA VWVEESPVQS LAWGRRTMAP
     SGYSQEDPLG LSIEGNEKKF PDDLREIFPE HSGDLSRENF SPCWFLLENH HATSFDDLKA
     GYSFLKRKVE GQKEGQLSFL KTHVSAVIDQ LDTLMNLKTK MEIEGEIDLA KRVNNLQGTI
     EKSIESSHEL FDDVLSRREK ADKARAALSV LNRYKFLFCL PTNIEKNASK NEFDIIVNDY
     ARAKNLYGKS EIPLIQKVLA EVDEIILEIR RKLHQKIQEM PQGVEQQKRF VKSLINLEIQ
     QVGTIQSEKL KIVDPAWGAI ESRARYIEQT FKNTYEEFQE RENSMKDNSK RDLNAPPIRV
     LFCEEITEIA TGQFPDLWRL GQSYFTGELR GINEPKPGNF KQIILNAIER FCSYVRAAIL
     PQNQKFQAVA SWAFTSSSQL QQFSTWLPTC LRYLRVSYAS LIRLDLPGEA LDIVLKLIDE
     LRLFCLTTIL KRAIDKVKKL HEKETWELTV PEFPGATALP SKLEEILVEV LDEGQQICLM
     MEVRENPLFD TPNSEGHREV AKIVETILSC FSNVVEELAT ERSDDEVQHM PKQLIGFPTN
     SSLLPHSINL TEAKSTISST ITITWEHRLL CCLANSAYCN KTFINSLGNL FVKFGYPIPK
     LALENSRTIV NNVFSNLLEI YVEHKSDPLV STIEPSMYIV SHFKWNRVEK FDNLSPYTHE
     CLDNVVSVYS EIFAVSPFLL RPILEQIIQT IAEELARLMS CVEEFNVIGK KQATLDIRMI
     RDVLRVYSNE RAKASFNEAL ESIPKLANDE NREVENLLAI IKQQMKLQLM CLTVLNP
//