ID   A0A1J1IZI6_9DIPT        Unreviewed;       588 AA.
AC   A0A1J1IZI6;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=CLUMA_CG018032, isoform A {ECO:0000313|EMBL:CRL05559.1};
GN   ORFNames=CLUMA_CG018032 {ECO:0000313|EMBL:CRL05559.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRL05559.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRL05559.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000256|ARBA:ARBA00001954};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; CVRI01000064; CRL05559.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1IZI6; -.
DR   STRING; 568069.A0A1J1IZI6; -.
DR   OrthoDB; 5473013at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008175; F:tRNA methyltransferase activity; IEA:UniProt.
DR   GO; GO:0043412; P:macromolecule modification; IEA:UniProt.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProt.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR027450; AlkB-like.
DR   InterPro; IPR037151; AlkB-like_sf.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR13069:SF21; ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8; 1.
DR   PANTHER; PTHR13069; UNCHARACTERIZED; 1.
DR   Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51471; FE2OG_OXY; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          194..301
FT                   /note="Fe2OG dioxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51471"
SQ   SEQUENCE   588 AA;  67372 MW;  E2CA80B06D212F02 CRC64;
     MKNLLKKTKA KEFPINADNS NIIFSSEPQE YLGILNAGLS NGINTEVLLE EVTKYAQLTD
     IRKDPKKVLE VMNGKSKLGQ NGAPLLMSFC ARISDENEVC PRQNFTQNKL PSGLILIEDC
     VSEDLEKKIL SSLSWSDNDD EKRNLKYRKV QHFGYEFIYG SNNVDPKSPL RRKIPDVCND
     IWKNLDQNIL PNFTPDQLTV NEYEPGHGIP PHCDTHSCFE DPIVSLSLGS SVVMEFRNPE
     SSKHLSVFLP QRSLLIMSGE SRYGWTHGIT PRMSDIVTNV DGILTVQSRQ KRTSFTFRKL
     RIPSSCSCSF PSLCDVKRKP DNIIEMHVTN ELAAKLEIEK VHKVYNEIGS HFSETRHSTW
     PNVEDFLKSL PEGSILCDVG CGNGKYLGVN EGIFKLGCDR SETLLQVCLQ RNFNIFQCDC
     LQLPVRDISI DACISIAVIH HLATEERRKQ AISEILRVLV IEGTALIYVW AKDQQKDNKK
     SSYLLQNQKQ EKSCNNQIEK TKIIFDENEI ELPIHQNRTQ FHHTNLLVPW KLKEKDIPKE
     QQKVFLRYYH VFEDGELENL CKEFKNVDII KSYYDQGNHC VVIKKTSF
//