ID A0A1J1J3T3_9DIPT Unreviewed; 937 AA.
AC A0A1J1J3T3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=CLUMA_CG019499, isoform A {ECO:0000313|EMBL:CRL06618.1};
GN ORFNames=CLUMA_CG019499 {ECO:0000313|EMBL:CRL06618.1};
OS Clunio marinus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Clunio.
OX NCBI_TaxID=568069 {ECO:0000313|EMBL:CRL06618.1, ECO:0000313|Proteomes:UP000183832};
RN [1] {ECO:0000313|EMBL:CRL06618.1, ECO:0000313|Proteomes:UP000183832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CVRI01000067; CRL06618.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1J3T3; -.
DR Proteomes; UP000183832; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048869; P:cellular developmental process; IEA:InterPro.
DR CDD; cd19187; PR-SET_PRDM1; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR016608; PRDM1.
DR InterPro; IPR044413; PRDM1_PR-SET.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16515; PR DOMAIN ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR16515:SF26; PR DOMAIN ZINC FINGER PROTEIN 1; 1.
DR Pfam; PF21549; PRDM2_PR; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR PIRSF; PIRSF013212; PRDM1; 2.
DR SMART; SM00317; SET; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 63..175
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 726..753
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 754..781
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 782..809
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 810..837
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 897..937
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 937 AA; 105783 MW; D6AF17873E5A193C CRC64;
MTETSLSRGE SPTNSMNQDY DITRMREDDF ERLAVYIVPD VPCERGIPGR AEKTLPRSLT
LKPSVVLSTP PQPIEGVWST GVIPKGTRFG PFEGHRTPSY PSDKSSWRYF WRIFKDSDFY
YLDGSDNSHA NWMRFVASAY NMKVMNLVAC QHQEHIYFYT IRDIMPNEEL MVWYCRDFAK
RMGYDIDPER ATYSICKEET LKKAAYAMPK TKISPEIAYN HMKYVMGLHI PASRRPQSPT
ASTTTNSPPR HQATHQTVLN LRESHEERDR SPIRIMIHEN GVTRVEETAK PVKEEASPKL
VVYEHQLTPN DGSVRSDEGY HSNGYHDEFT PPEDSSDSES EHNYVLDCSQ KTIEPKETVV
VAKANGECVD GKNDYRKVKM KMPLKYEFKN KNMTKDCEAE VADVAMTDVN EEEMTVVQTK
PATSTVIVLE SAPQNTPTIV PLTKSYYEAE TSSPPPQHHH HHHTSAAFMR YTPPTSSILE
TILTGNRLDQ DSSRRQPNAT PPPTSPTEMA YSYKKSQRYG NACSPDSSSN PQQPNCTSTS
NSHPLSPPQI LVPSRNVQQV VENSSNNNQA PTPPTLIYVN QSQFPPYESQ RTSPSYTYSI
YSNGNLVTAN SNNHSTSSTS STSSYSPPLN NGQYERLTSS TSSGAAMLPF TNGNQLPLSH
PLLTPLAPLQ HISTSRESPH SPPCSLSPDG ESYSRSGSPL SPGSPGSRGY KSLPYPLKKR
DGKMHYECNV CCKTFGQLSN LKVHLRTHSG ERPFRCNVCT KSFTQLAHLQ KHHLVHTGEK
PHQCDICKKR FSSTSNLKTH LRLHSGQKPY ECDLCPQKFT QFVHLKLHKR LHTNDRPYVC
QGCDKKYISA SGLRTHWKTT SCKPNNLEEE MALAAAATNE YLGDKEHADM ERERELYEYQ
HQQQQQSPQL HQQTTQNGGE TRPSVIESNQ PMIIECT
//
