ID   A0A1J1J3Y1_9DIPT        Unreviewed;      1169 AA.
AC   A0A1J1J3Y1;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   22-FEB-2023, entry version 15.
DE   SubName: Full=CLUMA_CG018922, isoform A {ECO:0000313|EMBL:CRL06166.1};
GN   Name=putative Hamartin {ECO:0000313|EMBL:CRL06166.1};
GN   ORFNames=CLUMA_CG018922 {ECO:0000313|EMBL:CRL06166.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRL06166.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRL06166.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CVRI01000066; CRL06166.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1J3Y1; -.
DR   STRING; 568069.A0A1J1J3Y1; -.
DR   OrthoDB; 4251017at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR007483; Hamartin.
DR   PANTHER; PTHR15154; HAMARTIN; 1.
DR   PANTHER; PTHR15154:SF2; HAMARTIN; 1.
DR   Pfam; PF04388; Hamartin; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        123..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          479..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          605..624
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          798..940
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        479..496
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        514..530
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1169 AA;  132822 MW;  D45D834CD4D03655 CRC64;
     MIENLFNDLE SHNVQTQENA KRELAEYFAS TKESWIVNGM IDYYSHTNSY RIFEVLVKVQ
     TPHDVNIFNK LQKCLQESSQ MQKRNALTLF GQIVRKQPTW LHKVVNHGFL KDLLKLLKNE
     RDVTIFMSGL LCIISLLPII PAPISAFLPD LFEIFNHLAA WLFHHASAIK ESELIHLQYG
     FYMLFNRLYG MYPCNFIDFL RNEYVNKQEK TAIFNHTIKP FLETVKIHPN LVMATKTTET
     SVSRFKKMEP HDVVVECSKY SIENDKPAPK SNFFDYPIYR SPMKPLEYTH LMVDLPPPLP
     AHATLASAKT VESKLESLWS PSYVVLATPP PSTTVPNTPT PTPVPMQPNF AITMPSTASH
     HQGDGSSPPQ LIEAAIEATP ETTPLKPEMK NIFRPYASNS QAVRNIWPKS SSLVQTSSPT
     SPMKKDSNQF QYSTAVDLPS TSNQNYNLDF TGNQKLFRIL SDRQQHPPSD VMSISQEDQE
     VNDINSSNSN HNMDIGGDGN GHQEMMDFDP TPESERENVD DDDDDEDADT TPPLGNQSIY
     QCVDYVRRVK RLRMYSHCMY SAGTSPADNT SYMPRASSSQ RMKRFNSWPN LKTSDVVIDC
     TKSKELNGSQ QHQESSSSPS DEAISAVSHF KKNDRNGNSK PNESLYKKIR NDLKAKPLEI
     VSKESKGTST VECWPALTAY DCLFYDTIFN DEGRPSTDVM TTVTTTTTTT TSVAVTKSRQ
     DAAYSESSTM SPALSPNEML DRYIQLSIKR KDSGDPRDQI GLLAIQLQFE KHRREIHAER
     NRRLLGKSRQ IRGLEQSNAT MIDQVARLST EITKLNRKAT ETRSMHQFEV KKFQEDIKLL
     SRKCNEEKEK NRQLQMEKES LELRLDDEQL LKRQSEHKNN LLTAELFDVK NLLEAANKEA
     ERGRSCRDQL VKLEAEMIIF NDARIKCQEK MEELHALKAR DAEMNILVDT YSHEIQELRR
     MLELKSSHAD VLRARVGELE QQVMKKDGCY AEQKRLMALI KDTNNEKMRI LEDKYSTQKA
     ILVRMEEHIL ELTRNQAAVT SPESERTADL VGYSSPLSIS LASSDGLSAS LRSTNELKSL
     QPLVVGNPVA SGSSGVFEHP STVVYPSTSQ PILQRQQSIH DDVPIAAIYQ ETQVSLPNVK
     SDYATSDNFH TISLNFFHCF NFTIAIVIT
//