ID A0A1J1J8G7_9DIPT Unreviewed; 528 AA.
AC A0A1J1J8G7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=CLUMA_CG020712, isoform A {ECO:0000313|EMBL:CRL07758.1};
DE Flags: Fragment;
GN ORFNames=CLUMA_CG020712 {ECO:0000313|EMBL:CRL07758.1};
OS Clunio marinus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Clunio.
OX NCBI_TaxID=568069 {ECO:0000313|EMBL:CRL07758.1, ECO:0000313|Proteomes:UP000183832};
RN [1] {ECO:0000313|EMBL:CRL07758.1, ECO:0000313|Proteomes:UP000183832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC 1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC ECO:0000256|RuleBase:RU000679}.
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DR EMBL; CVRI01000073; CRL07758.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1J8G7; -.
DR STRING; 568069.A0A1J1J8G7; -.
DR OrthoDB; 3682364at2759; -.
DR Proteomes; UP000183832; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.820; Acid-sensing ion channel domain; 1.
DR InterPro; IPR001873; ENaC.
DR PANTHER; PTHR11690:SF301; AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED; 1.
DR PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR Pfam; PF00858; ASC; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000679};
KW Ion transport {ECO:0000256|RuleBase:RU000679};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW ECO:0000256|RuleBase:RU000679};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT TRANSMEM 96..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CRL07758.1"
FT NON_TER 528
FT /evidence="ECO:0000313|EMBL:CRL07758.1"
SQ SEQUENCE 528 AA; 61704 MW; 1469F296CCCB5EB2 CRC64;
SKVTKVCSSS EEKKCYIRSK INFQKEIEET CQCLDPCDGV SYKGEKKRIV FAGKLVNRFE
KDTITKRSFD VRFKDEKFYP LILTKSYDNI ELISHIGGLI LLFVGFSFPS IVFATVRYGI
KCLIFKYDSM IATRIVKRSL KVLMAIPCVL GSFYIIIKFS FHDMANDIII EQGDDISVSQ
IAFPAVTYFA RQPWNYKFKG YSKFCVNSEL SSFDLFKTSW FQNQTAVWNE AHQVEFAEVM
TSRGTGISFN ILDFNDMFKT IEISSDFFYD RNITLRGGTK KFISDRPWKA FISSHGSLNL
ELTTMEIYSR KLEHAFFVHS PLELPLGLVD DDIIEFDEGK SLKILISPYM ITTDDDVKRL
KIEDRKCFLE NEKNLKLFKV YTKRNCELEC MSDHTNKTLG CVMLDVVRDR NTEVCDEKHK
IEGYKKVQVY TVQNLNCNCL EPCDMIRYDT QILEDKLRNL TTNETFLSFQ FKHSTFTPLK
RTLRHKRMDM FNFACGLLSF YCGLNLIQFL NVFLKFPQQM FRKICLRK
//
