ID   A0A1J4JBA5_9EUKA        Unreviewed;       772 AA.
AC   A0A1J4JBA5;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Sialidase domain-containing protein {ECO:0000259|Pfam:PF13088};
GN   ORFNames=TRFO_37430 {ECO:0000313|EMBL:OHS96416.1};
OS   Tritrichomonas foetus.
OC   Eukaryota; Metamonada; Parabasalia; Tritrichomonadida; Tritrichomonadidae;
OC   Tritrichomonas.
OX   NCBI_TaxID=1144522 {ECO:0000313|EMBL:OHS96416.1, ECO:0000313|Proteomes:UP000179807};
RN   [1] {ECO:0000313|Proteomes:UP000179807}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K {ECO:0000313|Proteomes:UP000179807};
RA   Benchimol M., Almeida L.G., Vasconcelos A.T., Perreira-Neves A., Rosa I.A.,
RA   Tasca T., Bogo M.R., de Souza W.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OHS96416.1}.
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DR   EMBL; MLAK01001178; OHS96416.1; -; Genomic_DNA.
DR   VEuPathDB; TrichDB:TRFO_37430; -.
DR   OrthoDB; 5482010at2759; -.
DR   Proteomes; UP000179807; Unassembled WGS sequence.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000179807};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        717..742
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          65..346
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
FT   REGION          625..711
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        637..691
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   772 AA;  86093 MW;  D930FDE0CEE03595 CRC64;
     MLCYFLASVL SVGVYREYVL YQPKFWNSAY YRIPALTTAN DGTLITATDM RWLNKNDLPA
     RISTIINYSP DNGITWTNPQ IISGPVRDVG DGDPALVVDR KTGCVLCLWT GDNGFRASTQ
     QKPQHLYVSR SFDNGRTWEE KRDVTHMIYS NLCTECDKDR YSWSAIFFSS GSALQLRDGR
     IMVSGVTRCW GTVRDYCVYT DDLGVTWTAS TSPAWWSGGD ESKFFENNDG AVVLSTRLSN
     GQKYRGFAWS YDRGLTFPRN KTMTDIWDSP CNGDVLRYTS TIDGYDKNRI LHTVTYVQAF
     PRRNVSILVS YDEGETWPVK KTLRDTPEEL GSYSSITLGH DGLIHIYYEK GTSSTDPDQF
     NMTVLTISLD WITDGQDVYK PPENLKWCVC EKNSSVCSEK CPSGYYHSSP KVFDNYIDTY
     WEYPTNMSYF FPIEVRDFTV NLSIPGLKHG KYEADPSLTK RPKVKIVGSA NESVTLEFHN
     VDIDTTIDVI LANRIIIDGT VLTVNCNISR VEVGSSIVKL VNGVGLKQAV GYVTIGQASS
     AKLLATTQTQ INIVNNLDNR YLEVGRGIEG VSGQETAGAP VKLSLPNEGS NSLFKIEGKW
     TDSEGSNLVL TGGKVVTSIA NQNKFKIEGS NPPTFEYEDD VQPTQQPTQQ PTQQPTQQPT
     QQPTQQPTQQ PTXXPTQQPT QQPTQQPTQQ PTEPITTPPS PTEDDAQSDE MSGRTKFTYL
     AIIGALSVTA VGLIIFAIAI VIKYKRVKNG TSVHDRSESA QSIFKTNLIY QS
//