ID A0A1J4JCT1_9EUKA Unreviewed; 375 AA.
AC A0A1J4JCT1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Actin {ECO:0000313|EMBL:OHS96904.1};
GN ORFNames=TRFO_02006 {ECO:0000313|EMBL:OHS96904.1};
OS Tritrichomonas foetus.
OC Eukaryota; Metamonada; Parabasalia; Tritrichomonadida; Tritrichomonadidae;
OC Tritrichomonas.
OX NCBI_TaxID=1144522 {ECO:0000313|EMBL:OHS96904.1, ECO:0000313|Proteomes:UP000179807};
RN [1] {ECO:0000313|EMBL:ARM19757.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=2006 {ECO:0000313|EMBL:ARM19757.1};
RA Rosa I.A., Brigido M.C., Santos E.O., Almeida L.G.P., Zingalli R.B.,
RA Vasconcelos A.T.R., Souza W., Benchimol M.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OHS96904.1, ECO:0000313|Proteomes:UP000179807}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K {ECO:0000313|EMBL:OHS96904.1,
RC ECO:0000313|Proteomes:UP000179807};
RA Benchimol M., Almeida L.G., Vasconcelos A.T., Perreira-Neves A., Rosa I.A.,
RA Tasca T., Bogo M.R., de Souza W.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ARM19757.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=2006 {ECO:0000313|EMBL:ARM19757.1};
RX PubMed=28369980; DOI=.1111/boc.201600050;
RA de Andrade Rosa I., Brigido M.C., de Oliveira Santos E., Gonzaga L.,
RA Zingali R.B., de Vasconcelos A.T., de Souza W., Benchimol M.;
RT "The costa of trichomonads: A complex macromolecular cytoskeleton structure
RT made of uncommon proteins.";
RL Biol. Cell 109:238-253(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the actin family.
CC {ECO:0000256|ARBA:ARBA00006752, ECO:0000256|RuleBase:RU000487}.
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DR EMBL; KX579523; ARM19757.1; -; Genomic_DNA.
DR EMBL; MLAK01001148; OHS96904.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4JCT1; -.
DR VEuPathDB; TrichDB:TRFO_02006; -.
DR OrthoDB; 3411884at2759; -.
DR Proteomes; UP000179807; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF387; ACTIN; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000179807}.
SQ SEQUENCE 375 AA; 41799 MW; 7C328100963C9E78 CRC64;
MADEVQTLVI DNGSGMCKAG FAGDEAPRSV FPSIVGRPKY VQAVAGGQNK DTYVGDEACA
KAGVLILKYP IEHGIVTNWD DMEKIWHHTF YNELRVDPAE HPVLLTEAPM NPKANREKMI
QLMFETFNVP SFYVGIQAVF SLYSSGRTTG IVFDAGDGVS HTVPIYEGYS LPHAIMRLNL
AGRDLTAWLQ KILNERGYTF TTSAEKEIVR DVKEKHAYVA LDYDAELQKA KTSSECDVSY
TLPDGNVITI ADERFRCPEL LFKPHMNGFE FDGIDQTLFD SIMKCDIDVR KDLYANIVLS
GGTTMFEGLP ERIEKEIIRL APPTMKVKVV APPERKYAVW IGGSILASLA TFPQMVITHD
EYNDAGPGIV HRKCF
//
