ID A0A1J4JMX1_9EUKA Unreviewed; 493 AA.
AC A0A1J4JMX1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=phosphopyruvate hydratase {ECO:0000256|ARBA:ARBA00012058};
DE EC=4.2.1.11 {ECO:0000256|ARBA:ARBA00012058};
GN ORFNames=TRFO_32832 {ECO:0000313|EMBL:OHT00471.1};
OS Tritrichomonas foetus.
OC Eukaryota; Metamonada; Parabasalia; Tritrichomonadida; Tritrichomonadidae;
OC Tritrichomonas.
OX NCBI_TaxID=1144522 {ECO:0000313|EMBL:OHT00471.1, ECO:0000313|Proteomes:UP000179807};
RN [1] {ECO:0000313|EMBL:ARM19916.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=32832 {ECO:0000313|EMBL:ARM19916.1};
RA Rosa I.A., Brigido M.C., Santos E.O., Almeida L.G.P., Zingalli R.B.,
RA Vasconcelos A.T.R., Souza W., Benchimol M.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OHT00471.1, ECO:0000313|Proteomes:UP000179807}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K {ECO:0000313|EMBL:OHT00471.1,
RC ECO:0000313|Proteomes:UP000179807};
RA Benchimol M., Almeida L.G., Vasconcelos A.T., Perreira-Neves A., Rosa I.A.,
RA Tasca T., Bogo M.R., de Souza W.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ARM19916.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=32832 {ECO:0000313|EMBL:ARM19916.1};
RX PubMed=28369980; DOI=.1111/boc.201600050;
RA de Andrade Rosa I., Brigido M.C., de Oliveira Santos E., Gonzaga L.,
RA Zingali R.B., de Vasconcelos A.T., de Souza W., Benchimol M.;
RT "The costa of trichomonads: A complex macromolecular cytoskeleton structure
RT made of uncommon proteins.";
RL Biol. Cell 109:238-253(2017).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC glyceraldehyde 3-phosphate: step 4/5. {ECO:0000256|ARBA:ARBA00005031}.
CC -!- SIMILARITY: Belongs to the enolase family.
CC {ECO:0000256|ARBA:ARBA00009604}.
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DR EMBL; KX579684; ARM19916.1; -; Genomic_DNA.
DR EMBL; MLAK01000953; OHT00471.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4JMX1; -.
DR VEuPathDB; TrichDB:TRFO_32832; -.
DR OrthoDB; 1093250at2759; -.
DR UniPathway; UPA00109; UER00187.
DR Proteomes; UP000179807; Unassembled WGS sequence.
DR GO; GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004634; F:phosphopyruvate hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd22962; DD_AtENO3-like; 1.
DR CDD; cd03313; enolase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR HAMAP; MF_00318; Enolase; 1.
DR InterPro; IPR000941; Enolase.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR020810; Enolase_C.
DR InterPro; IPR020809; Enolase_CS.
DR InterPro; IPR020811; Enolase_N.
DR NCBIfam; TIGR01060; eno; 1.
DR PANTHER; PTHR11902; ENOLASE; 1.
DR PANTHER; PTHR11902:SF1; ENOLASE; 1.
DR Pfam; PF00113; Enolase_C; 1.
DR Pfam; PF03952; Enolase_N; 1.
DR PRINTS; PR00148; ENOLASE.
DR SFLD; SFLDF00002; enolase; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SMART; SM01192; Enolase_C; 1.
DR SMART; SM01193; Enolase_N; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00164; ENOLASE; 1.
PE 3: Inferred from homology;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000179807}.
FT DOMAIN 54..188
FT /note="Enolase N-terminal"
FT /evidence="ECO:0000259|SMART:SM01193"
FT DOMAIN 200..493
FT /note="Enolase C-terminal TIM barrel"
FT /evidence="ECO:0000259|SMART:SM01192"
SQ SEQUENCE 493 AA; 53765 MW; 2659FA3C1252D63D CRC64;
MAESKAASAS EYMQKTHLTE SLQEVLNELL QTRPDDAYGE LTRLLRARSL PPTIDRVVGR
EVLDSRGNPT VEVDVYAKRY GKIFFAGRSS APSGASTGSN EARELRDTES PRYFGKGTLT
AARNVTEELS PALHGLKFDD LSALDRVIQN ADGTELKEHI GGNACTATSF ALAESAAKLN
HVQLFEYLAK QFHGEDMPQK FKLPTPFFNI LNGGKHAGGN LKLQEFMVSP KSDAPFPDQL
RMVAEVYQKL GEILVETYGV SAKNLGDEGG FAPLLNTPEE AISVIEKAIV AAGYEPGTDI
KLGLDAAASE FYNSDDKTYE VEVGVIKTGE EMIQYWKDLV EAHPAVVSIE DGLHETDYEN
WAKLNEELGD KIQLVGDDLY TTNPNTIRKG LEGKWANALL LKVNQIGTIS EAMEAARLIL
DAGQNVMVSH RSGETGNSLI ADLAVAIGAQ SIKTGSTARG ERIQKYTRLL QIYEYLVEND
MLDVGAGEGG EQE
//
