ID A0A1J4KHG7_9EUKA Unreviewed; 472 AA.
AC A0A1J4KHG7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=RAC family serine/threonine-protein kinase like protein {ECO:0000313|EMBL:OHT10643.1};
GN Name=pkbA {ECO:0000313|EMBL:OHT10643.1};
GN ORFNames=TRFO_04142 {ECO:0000313|EMBL:OHT10643.1};
OS Tritrichomonas foetus.
OC Eukaryota; Metamonada; Parabasalia; Tritrichomonadida; Tritrichomonadidae;
OC Tritrichomonas.
OX NCBI_TaxID=1144522 {ECO:0000313|EMBL:OHT10643.1, ECO:0000313|Proteomes:UP000179807};
RN [1] {ECO:0000313|Proteomes:UP000179807}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K {ECO:0000313|Proteomes:UP000179807};
RA Benchimol M., Almeida L.G., Vasconcelos A.T., Perreira-Neves A., Rosa I.A.,
RA Tasca T., Bogo M.R., de Souza W.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. AGC Ser/Thr
CC protein kinase family. RAC subfamily. {ECO:0000256|ARBA:ARBA00006935}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHT10643.1}.
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DR EMBL; MLAK01000605; OHT10643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4KHG7; -.
DR VEuPathDB; TrichDB:TRFO_04142; -.
DR Proteomes; UP000179807; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00821; PH; 1.
DR CDD; cd05123; STKc_AGC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000961; AGC-kinase_C.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR045270; STKc_AGC.
DR PANTHER; PTHR24351; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR PANTHER; PTHR24351:SF243; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OHT10643.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000179807};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 19..118
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 128..379
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 380..448
FT /note="AGC-kinase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51285"
SQ SEQUENCE 472 AA; 54429 MW; 7246A5CF6C3CF209 CRC64;
MFNLNCTKME DLPLLFSDIL SLEGELDVRD SPQSPWRKSF CRIIDATLEL FEDDIAASPF
VTIQINSSIT VEFDDDSKGK NNSFYFHVEK DNEFFYGFYA EKIEEARRWV DIIRALTMPQ
LKVTMDDFNI ISVLGRGFLG KVMLVEHKET KEMYAIKSVQ KKKLIESGRP HTIIAERNIM
MLIKNPFIIQ LHFAFQTPTK FYLGLEYAPG GELFYHMEHI GLIPVDDARL YVAEISIALE
HLHKYGIVYR DLKPENVLLD AQGHVKLTDF GLAKDLCEVQ NTSTFCGTNH YLAPEIIRNE
PYSYEIDWWA LGILLCEMLT GVTPFDGESR AKMFDSITQD EPMLPTDIDN DAGDLILKLL
TKNPKERPSF EDIAAHKFFE CLDWELVVDR RYVPNFVPEE IERPTMYFPP EFTQEDAIDS
TIESYPAEDN MNVTGFSFFA PNVMDDGAKE VDMDVMDTDM LEEYQKLGET EL
//
