ID A0A1J4KWE7_9EUKA Unreviewed; 291 AA.
AC A0A1J4KWE7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha {ECO:0000256|ARBA:ARBA00040965};
DE EC=2.5.1.58 {ECO:0000256|ARBA:ARBA00012702};
DE EC=2.5.1.59 {ECO:0000256|ARBA:ARBA00012700};
DE AltName: Full=CAAX farnesyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043086};
DE AltName: Full=FTase-alpha {ECO:0000256|ARBA:ARBA00042436};
DE AltName: Full=Ras proteins prenyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00041392};
DE AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043219};
GN Name=FTA {ECO:0000313|EMBL:OHT15208.1};
GN ORFNames=TRFO_42665 {ECO:0000313|EMBL:OHT15208.1};
OS Tritrichomonas foetus.
OC Eukaryota; Metamonada; Parabasalia; Tritrichomonadida; Tritrichomonadidae;
OC Tritrichomonas.
OX NCBI_TaxID=1144522 {ECO:0000313|EMBL:OHT15208.1, ECO:0000313|Proteomes:UP000179807};
RN [1] {ECO:0000313|Proteomes:UP000179807}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K {ECO:0000313|Proteomes:UP000179807};
RA Benchimol M., Almeida L.G., Vasconcelos A.T., Perreira-Neves A., Rosa I.A.,
RA Tasca T., Bogo M.R., de Souza W.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC family. {ECO:0000256|ARBA:ARBA00006734}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHT15208.1}.
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DR EMBL; MLAK01000259; OHT15208.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4KWE7; -.
DR VEuPathDB; TrichDB:TRFO_42665; -.
DR OrthoDB; 20949at2759; -.
DR Proteomes; UP000179807; Unassembled WGS sequence.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR InterPro; IPR002088; Prenyl_trans_a.
DR PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11129:SF1; PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA; 1.
DR Pfam; PF01239; PPTA; 2.
DR SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR PROSITE; PS51147; PFTA; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW Reference proteome {ECO:0000313|Proteomes:UP000179807};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:OHT15208.1}.
SQ SEQUENCE 291 AA; 34258 MW; E8E97D2263E19BAD CRC64;
MMKVNFDDEK WADLTPIPNP GDENGPFGIR YGGSYGTTME YFRALMNINE LSERALEVVT
FLCQANPSNP APFWYRQRIL EKIGYNFDEE LEFTTKLANQ YLKPYQIWNH RQWLVSKCEN
PPDETGFMKF ILKLDCKNFH AWEYFYWLAE TYDRMQWLFD QATLQVQLNS NNNSAWSMRY
SSMQKINLTV NEDIQFVLDE YKKNPESRSI ASYLLAYVKL DTSIIQKVKD VLNEILSQNG
QIVGTLTLLA QIAEFEGNHD EYCHIADKII ELDEMHANFW NLMKSDSSKF K
//
