ID A0A1J4MIG0_9CRYT Unreviewed; 342 AA.
AC A0A1J4MIG0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Meiotic recombination protein DMC1-like protein {ECO:0000313|EMBL:OII74042.1};
GN ORFNames=cubi_02844 {ECO:0000313|EMBL:OII74042.1};
OS Cryptosporidium ubiquitum.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=857276 {ECO:0000313|EMBL:OII74042.1, ECO:0000313|Proteomes:UP000186176};
RN [1] {ECO:0000313|EMBL:OII74042.1, ECO:0000313|Proteomes:UP000186176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=39726 {ECO:0000313|EMBL:OII74042.1};
RA Liu S., Roellig D.M., Guo Y., Li N., Frace M.A., Tang K., Zhang L.,
RA Feng Y., Xiao L.;
RT "Reductive evolution of mitochondrial metabolism and differential evolution
RT of invasion-related proteins in Cryptosporidium.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RecA family. DMC1 subfamily.
CC {ECO:0000256|ARBA:ARBA00008897}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OII74042.1}.
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DR EMBL; LRBP01000013; OII74042.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4MIG0; -.
DR VEuPathDB; CryptoDB:cubi_02844; -.
DR OrthoDB; 5477610at2759; -.
DR Proteomes; UP000186176; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011940; Dmc1.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR NCBIfam; TIGR02238; recomb_DMC1; 1.
DR PANTHER; PTHR22942:SF30; MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG; 1.
DR PANTHER; PTHR22942; RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47794; Rad51 N-terminal domain-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003422};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003422}.
FT DOMAIN 101..272
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 279..342
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
SQ SEQUENCE 342 AA; 37210 MW; E12233BE5F315B22 CRC64;
MSTFCQSKSV AKQVSAKGSE EEAFVEIDKL QSAGINVADI NKLKTAGLCT VLSIIQATKK
ELCNIKGLSE AKVEKIVEAA QKLDQSSSFQ SGSEVMSRRQ NILRITTGSE QFDKMLMGGF
ESMCITEIFG ENRCGKTQIC HTLCVAAQLP LEMNGGNGKV CFIDTEGTFR PERIVKIAER
FGVQGDAALD NIMYARAYTH EHLNQLISAA AGKMIEEKFA LLIVDSIIAL FRTEFSGRGE
LAERQQILNK TLSKLNKLAD QFNIAIVMTN HVMADPAGGM SFMPNVAKPV GGHVIGHASH
VRLSLRKGKG EQRVCKVYGS PHLPESECVI QLSDGGIIDP ID
//
