ID A0A1J4MJ44_9CRYT Unreviewed; 760 AA.
AC A0A1J4MJ44;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=cubi_00849 {ECO:0000313|EMBL:OII72877.1};
OS Cryptosporidium ubiquitum.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=857276 {ECO:0000313|EMBL:OII72877.1, ECO:0000313|Proteomes:UP000186176};
RN [1] {ECO:0000313|EMBL:OII72877.1, ECO:0000313|Proteomes:UP000186176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=39726 {ECO:0000313|EMBL:OII72877.1};
RA Liu S., Roellig D.M., Guo Y., Li N., Frace M.A., Tang K., Zhang L.,
RA Feng Y., Xiao L.;
RT "Reductive evolution of mitochondrial metabolism and differential evolution
RT of invasion-related proteins in Cryptosporidium.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OII72877.1}.
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DR EMBL; LRBP01000018; OII72877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4MJ44; -.
DR VEuPathDB; CryptoDB:cubi_00849; -.
DR OrthoDB; 5474026at2759; -.
DR Proteomes; UP000186176; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 120..317
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 356..512
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT COILED 43..98
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 713..747
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 760 AA; 87738 MW; 40A7C0AE79013AA4 CRC64;
MGVTEGRLKG ETAKKNEKWK QSSLNNFMGL SKRKLVESED DFDNEEQLRV KELENNIEAE
KAQEDKIKEL FCRYKLKVDN LKREDKVIEE DVAELKKGLR WGLSYLKLED YRRGQKDAIE
KLVCERKDVV LILPTGGGKS LTYQLPSLLR EYQKQVKVIP SLSKGMVTVV VSPLIALIED
QINSLRKWGV KSNGLSSTII QKSDPSQSIN NALEELYADL EKKIPTNSII YVTPESFGTE
KVLGCLYKLY MNGNLYCFAI DEAHCISEWG HDFRTAYRRL NQIKNIFSDV PILACTATAS
PKVQRDIKTV LNLRDPYISI NSFNRPNIHY TAYNIDTNDY LTDLSLEEII LNGVLYMQEY
FKRLDSKETP IGIVYVNSRK SSEHLSQYLS NKGIPSKSYH AGLSLKIRTQ IQNEWLENKI
HVLVGTIAFG MGVHKPNVRF VIHSSIPDSI DSYYQQSGRA GRDSKFSKAM LFFSKKDITC
LKSIKRKSLQ YLFMKSQQKA QQAFEKFQDN LQSIVEFAQC NNSEYQEIDS YYETDYYPEN
TIDNNNVNRS SINHISGFNS NLKPQDPSNY QIRINKYGQC RRKFLLGYFG EKLSKENYSC
SYYMPCCDVC DSKDKKQDKQ ESFMSFVSSK IHRKNSPSKL FSKDEYINSF RNQPFKQEFS
FEYDQIQELD FDCIQSNKAG PSSFSSAFKS AKSFLKVEYK VSKNSFQSAL KMNNQLKSKG
LSYLERLEAL EEQEAKSEEK SSTLSSKFNI IRNSLKKKRN
//
