ID   A0A1J4MMQ5_9CRYT        Unreviewed;       501 AA.
AC   A0A1J4MMQ5;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=RNA methylase {ECO:0000313|EMBL:OII75478.1};
GN   ORFNames=cubi_01999 {ECO:0000313|EMBL:OII75478.1};
OS   Cryptosporidium ubiquitum.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=857276 {ECO:0000313|EMBL:OII75478.1, ECO:0000313|Proteomes:UP000186176};
RN   [1] {ECO:0000313|EMBL:OII75478.1, ECO:0000313|Proteomes:UP000186176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=39726 {ECO:0000313|EMBL:OII75478.1};
RA   Liu S., Roellig D.M., Guo Y., Li N., Frace M.A., Tang K., Zhang L.,
RA   Feng Y., Xiao L.;
RT   "Reductive evolution of mitochondrial metabolism and differential evolution
RT   of invasion-related proteins in Cryptosporidium.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OII75478.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LRBP01000001; OII75478.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J4MMQ5; -.
DR   VEuPathDB; CryptoDB:cubi_01999; -.
DR   OrthoDB; 5488599at2759; -.
DR   Proteomes; UP000186176; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR000241; RlmKL-like_Mtase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR   PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR   Pfam; PF01170; UPF0020; 1.
DR   PIRSF; PIRSF017259; tRNA_mtfrase_TRM11; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:OII75478.1}; RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT   DOMAIN          231..365
FT                   /note="UPF0020"
FT                   /evidence="ECO:0000259|Pfam:PF01170"
SQ   SEQUENCE   501 AA;  57945 MW;  D3FDAA26B890AF7D CRC64;
     MPLYLVWFVL HPDYHEFRLQ ELESLAGCFG IEKNKLWVSN LPNYVSWKGN EYNRPLANDH
     SNSFAWVYLP KEDIALRILE RSVLVRGFME VWASGPDHEK VKQILKQDEH VKSEFLRNYI
     HDNVDFSWKV RSIGKKLSRP EQVSRMNDYG FLFKGTEKVN LKEPSLSLGI FEDWRCINWE
     DEHSKEGISK EEISKVKSDL KRVYLGRIIG FQSCNDLEDK SLWWLKYTLN KRPILGPTTM
     DNELAFIMCN IAQVKKNDVV FDPFCGTGGI LISASHFGAT CFGSDLDLRV INGWFCSYVN
     PHMIKNNTIK EDHPRSIYSN FDYYKLQRPG IIRMDISQNS IRRSWIDAIV CDPPYGIRAT
     SRTTNSNQNQ INEQREDSSY SGNNYIHSFI QDYNYRKKTS SYSTPDMSNT HPSVGKNNFG
     SLQPIDDMIF DLLSFASKTL VNDGHLVFLL PLLASDANIV ISNLIDAWKH IFSIDFPYMQ
     TLGGGLGRLL VHMKLLKKKE K
//