ID   A0A1J4NMX4_9ACTN        Unreviewed;       616 AA.
AC   A0A1J4NMX4;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Polyketide synthase {ECO:0000313|EMBL:OIJ63482.1};
DE   Flags: Fragment;
GN   ORFNames=WN71_033780 {ECO:0000313|EMBL:OIJ63482.1};
OS   Streptomyces mangrovisoli.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1428628 {ECO:0000313|EMBL:OIJ63482.1, ECO:0000313|Proteomes:UP000034196};
RN   [1] {ECO:0000313|EMBL:OIJ63482.1, ECO:0000313|Proteomes:UP000034196}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MUSC149T {ECO:0000313|Proteomes:UP000034196};
RA   Lee L.-H., Ser H.-L.;
RT   "Genome sequence of Streptomyces mangrovisoli MUSC 149.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OIJ63482.1}.
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DR   EMBL; LAVA02000102; OIJ63482.1; -; Genomic_DNA.
DR   RefSeq; WP_071369911.1; NZ_LAVA02000102.1.
DR   AlphaFoldDB; A0A1J4NMX4; -.
DR   STRING; 1428628.WN71_033780; -.
DR   OrthoDB; 2472181at2; -.
DR   Proteomes; UP000034196; Unassembled WGS sequence.
DR   CDD; cd05235; SDR_e1; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR010080; Thioester_reductase-like_dom.
DR   NCBIfam; TIGR01746; Thioester-redct; 1.
DR   PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR   PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034196}.
FT   DOMAIN          42..275
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:OIJ63482.1"
SQ   SEQUENCE   616 AA;  67512 MW;  2482E27B5BBCB301 CRC64;
     TPAPHSTARP EDLAQILADL ALADRLPFTA APEPVPPRRI LLTGATGFLG GHMLLDLLRH
     SDAHVVCLVR AEDEAAAVER LGAQLRSYRL PWSAEVRRRV TVLPGDLREP RLGLSEERWT
     TLAHEVDSVV GVGAAVDFLR GYRSLRASNV LGTLALAELA ATGRPKPLHH ISSVAVFNEV
     GIPSMGEDDP LAHVDRLVSG YDQSKWAAEV ALRRARDHGL VVTALRPGGI SGHTRTGAYN
     PLDLSSGLVS AFGRFRTVPA FRYLNAAPVD WVSRVAVAAV CTPDAWGFDY NLTGVPNTLD
     DVVRDMAFGG MHVRVQDWDE WRADTLARLD AEPVPELAFL SRVLQSPTAL KLCEATLRGP
     AAEAARTDRL VAALGLPPAA RYDSRAQLKT FERLADDGLA RLPRGDDQPY LWFQETTEGA
     VGPVGGAADT ECSMALTLSI ASMYQLVRER RVDVTGTVTC AAVHAAPLTV ERGDIWVRPE
     EGIPLQHGMR HQLLTYRLTL TDQDGGRWWL EGRKHARARR DLWRQTRALS VEIGPEGEAA
     ALRGEVVVPA DSYVRDQIDG IRVDPRLTDR EKRAAKLTWL AWFGLEMGRG LLAPFTRAAA
     DLLDLRRTPT LTEHQR
//