ID A0A1J4NPG6_9ACTN Unreviewed; 549 AA.
AC A0A1J4NPG6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:OIJ64255.1};
GN ORFNames=WN71_029240 {ECO:0000313|EMBL:OIJ64255.1};
OS Streptomyces mangrovisoli.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1428628 {ECO:0000313|EMBL:OIJ64255.1, ECO:0000313|Proteomes:UP000034196};
RN [1] {ECO:0000313|EMBL:OIJ64255.1, ECO:0000313|Proteomes:UP000034196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC149T {ECO:0000313|Proteomes:UP000034196};
RA Lee L.-H., Ser H.-L.;
RT "Genome sequence of Streptomyces mangrovisoli MUSC 149.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIJ64255.1}.
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DR EMBL; LAVA02000083; OIJ64255.1; -; Genomic_DNA.
DR RefSeq; WP_046589509.1; NZ_LAVA02000083.1.
DR AlphaFoldDB; A0A1J4NPG6; -.
DR STRING; 1428628.WN71_029240; -.
DR OrthoDB; 5241017at2; -.
DR Proteomes; UP000034196; Unassembled WGS sequence.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR007887; MecA_N.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF05223; MecA_N; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000034196}.
FT DOMAIN 59..170
FT /note="NTF2-like N-terminal transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF05223"
FT DOMAIN 274..545
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 549 AA; 55743 MW; 9BC6959FC642B6B2 CRC64;
MNRAAKVGVA GACTTLLVLG GFGTYNLLHG LTSATGGDGA GQGFSQTAVS KSPPSAEKAE
KLTRAFLDSW SQQRLDGAAS DTDQPGAASS ALADYKTGLG LTKLSFTDVR SAGPSTATVG
ATKVTFDVTA HVKGGTWSYP SAVAVLQDTD GDAAVHWNNS VLYPGLQGDQ ALTAGELPAG
AGSAKVVASD GKTDLSTFPS LTDIVASIRK NGTPKGGTTG TGVAVVDGDG TGVETLKVFV
KGKSPVVRTT IDAHLQEVAE SAVKDAHLQQ KPAGTVALDW RTGHILAIAH TGDDGDIAIN
GIKSPGSTMK IITSAALFDQ AGLTMNSPAP CTDSLMANSQ LFHNDAGVKP NEKATIAQAF
TVSCNTAFIK DGFHYLVNGG DASALHNEAV NVFGMGSWSI GGGVATTDPS IPDDVQGGDQ
AAQFIGQGRV TATPLFMASV AATVRNVGFR QPVILPDQHQ QTAPRAISAR TAGYLQTMMR
SVATSGTAAP RLGGLAGVGA KTGTAEEGDH TNGWLTAYNS QIAVAALVEG GSSGVDSAGY
VVRELLTRS
//
