ID A0A1J4NTG4_9ACTN Unreviewed; 306 AA.
AC A0A1J4NTG4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Flap endonuclease {ECO:0000313|EMBL:OIJ64517.1};
GN ORFNames=WN71_028555 {ECO:0000313|EMBL:OIJ64517.1};
OS Streptomyces mangrovisoli.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1428628 {ECO:0000313|EMBL:OIJ64517.1, ECO:0000313|Proteomes:UP000034196};
RN [1] {ECO:0000313|EMBL:OIJ64517.1, ECO:0000313|Proteomes:UP000034196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC149T {ECO:0000313|Proteomes:UP000034196};
RA Lee L.-H., Ser H.-L.;
RT "Genome sequence of Streptomyces mangrovisoli MUSC 149.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIJ64517.1}.
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DR EMBL; LAVA02000079; OIJ64517.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4NTG4; -.
DR STRING; 1428628.WN71_028555; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000034196; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000313|EMBL:OIJ64517.1};
KW Hydrolase {ECO:0000313|EMBL:OIJ64517.1};
KW Nuclease {ECO:0000313|EMBL:OIJ64517.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000034196}.
FT DOMAIN 3..275
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 306 AA; 32814 MW; 34C503557E0AEA2E CRC64;
MTGRLMLLDT ASLYFRAYFG VPESVKAPDG TPVNAVRGLL EFIDRLVKDH RPDELVACMD
ADWRPQWRVD LIPSYKAHRV AEEHASGPDE EEVPDTLSPQ VPVIEAVLDA VGIARVGVPG
YEADDVIGTF TAGASGPVDI VTGDRDLYQL VDDARGIRVL YPIKGVGTLQ LTDEAALREK
YGVDGRGYVD LALLRGDPSD GLPGVPGIGE KTAAKLLAEF GDLDGIMAAV DDPKAKLTPS
QRKRLTEARP YVAVAPKVVR VASDVPLPQV DTRLPHAPRD PAGLTELAAR WGLGSSLQRL
LSTLGA
//
