ID A0A1J4P2M2_9ACTN Unreviewed; 497 AA.
AC A0A1J4P2M2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
DE Flags: Fragment;
GN ORFNames=WN71_004265 {ECO:0000313|EMBL:OIJ69007.1};
OS Streptomyces mangrovisoli.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1428628 {ECO:0000313|EMBL:OIJ69007.1, ECO:0000313|Proteomes:UP000034196};
RN [1] {ECO:0000313|EMBL:OIJ69007.1, ECO:0000313|Proteomes:UP000034196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC149T {ECO:0000313|Proteomes:UP000034196};
RA Lee L.-H., Ser H.-L.;
RT "Genome sequence of Streptomyces mangrovisoli MUSC 149.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIJ69007.1}.
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DR EMBL; LAVA02000010; OIJ69007.1; -; Genomic_DNA.
DR RefSeq; WP_046584707.1; NZ_LAVA02000010.1.
DR AlphaFoldDB; A0A1J4P2M2; -.
DR STRING; 1428628.WN71_004265; -.
DR OrthoDB; 140919at2; -.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000034196; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd05015; SIS_PGI_1; 1.
DR CDD; cd05016; SIS_PGI_2; 1.
DR HAMAP; MF_00473; G6P_isomerase; 1.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035476; SIS_PGI_1.
DR InterPro; IPR035482; SIS_PGI_2.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612};
KW Reference proteome {ECO:0000313|Proteomes:UP000034196}.
FT NON_TER 497
FT /evidence="ECO:0000313|EMBL:OIJ69007.1"
SQ SEQUENCE 497 AA; 55033 MW; 63C89BEBA806C0D5 CRC64;
MNADGRTRLD QRPEWTALTE HREALGDVQL RELFDADPER GERCTLQVGD LHIDYSKHLV
TDDTLRLLRE LAAATDVFGL RDAMFRGEKI NTTEDRAVLH TALRAPRDAV VEVDGQNVVP
GVHAVLDKMA HFAERVRSGA WTGHTGKRIK NVVNIGIGGS DLGPAMAYEV LRSYTDRGLT
VRFVSNVDGA DLHEAVRDLD AAETLFIVAS KTFTTIETIT NATSAREWLL GELKAGQEAV
AQHFVALSTN EDKVTGFGID PANMFEFWDW VGGRYSYDSA IGLSLMIAIG PERFREMLDG
FHLVDEHFRT APAEANVPLL MGLLGIWYGN FHDAQSHAVL PYSHYLSKFT AYLQQLDMES
NGKYVGRDGR EVDWQTGPVV WGTPGTNGQH AYYQLIHQGT KLIPADFIGF ARPVDDLLPG
FVAQHDLLMA NFFAQTQALA FGKTPEEVRA EGVPEELVPH KTFKGNHPTT TVLAEALTPS
VLGQLIALYE HKVFVQG
//
