ID A0A1J4PWB3_9ACTN Unreviewed; 608 AA.
AC A0A1J4PWB3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=LytR family transcriptional regulator {ECO:0000313|EMBL:OIK24398.1};
GN ORFNames=VT52_027430 {ECO:0000313|EMBL:OIK24398.1};
OS Streptomyces malaysiense.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1428626 {ECO:0000313|EMBL:OIK24398.1, ECO:0000313|Proteomes:UP000034838};
RN [1] {ECO:0000313|Proteomes:UP000034838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC136T {ECO:0000313|Proteomes:UP000034838};
RA Lee L.H., Chan K.-G.;
RT "Genome sequencing of Streptomyces sp. MUSC136T.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OIK24398.1, ECO:0000313|Proteomes:UP000034838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC136T {ECO:0000313|Proteomes:UP000034838};
RA Lee L.-H., Ser H.-L.;
RT "Genome sequence of Streptomyces malaysiense MUSC 136.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LytR/CpsA/Psr (LCP) family.
CC {ECO:0000256|ARBA:ARBA00006068}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIK24398.1}.
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DR EMBL; LBDA02000069; OIK24398.1; -; Genomic_DNA.
DR RefSeq; WP_046426257.1; NZ_LBDA02000069.1.
DR AlphaFoldDB; A0A1J4PWB3; -.
DR OrthoDB; 9782542at2; -.
DR Proteomes; UP000034838; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.630.190; LCP protein; 1.
DR InterPro; IPR027381; LytR/CpsA/Psr_C.
DR InterPro; IPR004474; LytR_CpsA_psr.
DR NCBIfam; TIGR00350; lytR_cpsA_psr; 1.
DR PANTHER; PTHR33392; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR PANTHER; PTHR33392:SF6; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR Pfam; PF13399; LytR_C; 1.
DR Pfam; PF03816; LytR_cpsA_psr; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000034838};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 135..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 210..372
FT /note="Cell envelope-related transcriptional attenuator"
FT /evidence="ECO:0000259|Pfam:PF03816"
FT DOMAIN 487..580
FT /note="LytR/CpsA/Psr regulator C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13399"
FT REGION 1..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 63990 MW; D594891E0D4326BD CRC64;
MDAQGRGRAD NIDPADQWVL NPNTGEYELQ LPPSGTQSVP GPRKPSAPDG DGARRRRRND
MAPGETREMS TVPAQDGGRE GGGTRTQAGG RTRDTARAGD VPPPRTSRRR GTEPEGAPGR
RGRRPVKKKS KAKKVLAWTA GGTAFALVAV GAAGYLYLKH LEGNISSTDV GDAGSKGFSK
DEAFNLLIIG TDKRTGKGNE GYGDSGSVGH ADTDILLHVS KDRTNATALS IPRDLIVNVP
DCPTKQPDGS SKVIPGTDNV RFNTSLGQDG RDPGCTMRTV EEVTGIHVDH FMMADFNAVK
TLTSAVGGVE VCVAHPVDDK ESHLKLPAGK SVVEGEQALA FVRTRHSFGN QGDLDRIKVQ
QQFLGSLMRK MSSGDTLSNP SKLMDLAEAA TKALTVDTGI KSINTLKDIA LELKKVPPKN
ITFTTVPVVD NPAEKVHATV VLNQSAAPAV FRAIQDDVSF TDVKRKQKAA KDAQAARLKG
TRSAPGDVRV RILNSEAAPG SAQAVLDWLQ NSEGVLKSEN AGNASAGLRK TTLEYAPDQA
AQARELAALM GLPGSALKPG SSVVNSQGLP AMTLTLGKDF KGAGTPITAP DTAPKVDKST
ADEVKCAS
//
