ID A0A1J4Q2M1_9ACTN Unreviewed; 441 AA.
AC A0A1J4Q2M1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=ATP-binding protein {ECO:0000313|EMBL:OIK26368.1};
GN ORFNames=VT52_016285 {ECO:0000313|EMBL:OIK26368.1};
OS Streptomyces malaysiense.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1428626 {ECO:0000313|EMBL:OIK26368.1, ECO:0000313|Proteomes:UP000034838};
RN [1] {ECO:0000313|Proteomes:UP000034838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC136T {ECO:0000313|Proteomes:UP000034838};
RA Lee L.H., Chan K.-G.;
RT "Genome sequencing of Streptomyces sp. MUSC136T.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OIK26368.1, ECO:0000313|Proteomes:UP000034838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC136T {ECO:0000313|Proteomes:UP000034838};
RA Lee L.-H., Ser H.-L.;
RT "Genome sequence of Streptomyces malaysiense MUSC 136.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC {ECO:0000256|ARBA:ARBA00038093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIK26368.1}.
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DR EMBL; LBDA02000036; OIK26368.1; -; Genomic_DNA.
DR RefSeq; WP_046423453.1; NZ_LBDA02000036.1.
DR AlphaFoldDB; A0A1J4Q2M1; -.
DR OrthoDB; 9766527at2; -.
DR Proteomes; UP000034838; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR Pfam; PF02562; PhoH; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:OIK26368.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000313|EMBL:OIK26368.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000034838};
KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT DOMAIN 13..140
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
SQ SEQUENCE 441 AA; 48353 MW; DE3AAB44CCB85087 CRC64;
MVTSTKRRKP DRRTYVLDTS VLLADPSALT RFEEHEVVLP IVVVTELEAK RHHPELGYFA
RQALRLLDDY RVRCGRLDSP IPIGDLGGTM RVELNHSDPS VLPTGYRLGD NDSRILAVAR
NLQAEGFDVT VVSKDLPLRI KASSVGLLAE EYRAELAITE NSGWTGMTEL TLPGEQVDVL
FEAGHVYVPQ ASELPVHTGL TIQSERGKAL GRITAEGNVR LVRGDREAFG IKGRSAEQRI
ALDLLLDPDV GIVSMGGRAG TGKSALALCA GLEAVLERRQ HQKVMVFRPL YAVGGQELGY
LPGTEAEKMS PWAQAVFDTL SAVTSREVIE EVTARGMLEV LPLTHIRGRS LHDAFVIVDE
AQSLERNVLL TVLSRIGANS RVVLTHDVAQ RDNLRVGRYD GVVAVVEKLK GHPLFAHVTL
TRSERSQIAA LVTEMLEDGH I
//
