ID A0A1J4QCQ3_9GAMM Unreviewed; 651 AA.
AC A0A1J4QCQ3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=endopeptidase La {ECO:0000256|PROSITE-ProRule:PRU01122};
DE EC=3.4.21.53 {ECO:0000256|PROSITE-ProRule:PRU01122};
GN ORFNames=BFR47_06955 {ECO:0000313|EMBL:OIN04332.1};
OS Oceanisphaera psychrotolerans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Oceanisphaera.
OX NCBI_TaxID=1414654 {ECO:0000313|EMBL:OIN04332.1, ECO:0000313|Proteomes:UP000243073};
RN [1] {ECO:0000313|EMBL:OIN04332.1, ECO:0000313|Proteomes:UP000243073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LAM-WHM-ZC {ECO:0000313|EMBL:OIN04332.1,
RC ECO:0000313|Proteomes:UP000243073};
RA Zhuo S., Ruan Z.;
RT "Draft Genome Sequence of Oceanisphaera psychrotolerans, isolated from
RT coastal sediment samples.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01122};
CC -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIN04332.1}.
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DR EMBL; MDKE01000069; OIN04332.1; -; Genomic_DNA.
DR RefSeq; WP_071474108.1; NZ_MDKE01000069.1.
DR AlphaFoldDB; A0A1J4QCQ3; -.
DR STRING; 1414654.BFR47_06955; -.
DR OrthoDB; 9758568at2; -.
DR Proteomes; UP000243073; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR041699; AAA_32.
DR InterPro; IPR046844; Lon-like_helical.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR027065; Lon_Prtase.
DR InterPro; IPR046843; LonB_AAA-LID.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10046; ATP DEPENDENT LON PROTEASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10046:SF49; LON PROTEASE HOMOLOG-RELATED; 1.
DR Pfam; PF13654; AAA_32; 1.
DR Pfam; PF05362; Lon_C; 1.
DR Pfam; PF20436; LonB_AAA-LID; 1.
DR Pfam; PF20437; LonC_helical; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS51786; LON_PROTEOLYTIC; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01122};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01122}; Serine protease {ECO:0000256|PROSITE-ProRule:PRU01122}.
FT DOMAIN 416..613
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|PROSITE:PS51786"
FT ACT_SITE 508
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
FT ACT_SITE 551
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
SQ SEQUENCE 651 AA; 72763 MW; 0A1D2D07E2F81AA4 CRC64;
MQPLSPVELN PVFNLPELAT LNEVPCLPFS ALQARVDSAF STLSELNAVN PVLLLNGFPG
ADYEELVQDL VRKHAKHADL FDLCYAENLH HPQKPIWLRL KAGTGIEFCE LVGQLLELSS
RHLEAEHVVQ RILKKQGNDE KIADYLSLLS QHVAAGQGFS HPVLINLMVH RHDQTIPIVY
ARQFTPEQLF GAIHFQTEQG SVFSHHHLLE PGLIHQANGG YLIVPIEELL DQPNLWFRLK
NALASRRVEW SRSAEMASFY FQPEPPPLDI HLILVGDRLS VAELYLLDRE LDTLAFLRAD
IIPEWDVRED LPSYLGFLSH LRQKHQLLDM DGSAILRLCR YGCRLTEHQH RLSLVESQLV
AMMQLSDVIA RREQSELITE AHVLLAQQEQ DHRLSFLVEQ SDLGVRDGQY LLQTSGKIVG
QINGLSVIQI TGHPYDFGEP VRLTATVHLG DGDVVDIERK ADLAGHIHAK AMMIIHGYLS
NLFGAEHPSP LSANLVFEQS YHEIDGDSAS LTGLCALLSA LAKEPIYQHF AVTGAVDQFG
HVQPVGGVNE KIEGFFRLCK IQGLTGEQGV LIPASNRLQL NLSDEVSAAI QAGQFHIYPV
AHVEQAIELL TGSVAGDVEQ PDTLFGRIRD RLDELNGHTV ESGFLRRLFR R
//
