ID A0A1J4UQ00_9ARCH Unreviewed; 148 AA.
AC A0A1J4UQ00;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Transcription elongation factor Spt5 {ECO:0000256|HAMAP-Rule:MF_00950};
GN Name=spt5 {ECO:0000256|HAMAP-Rule:MF_00950};
GN ORFNames=AUJ15_00410 {ECO:0000313|EMBL:OIO26906.1};
OS Candidatus Micrarchaeota archaeon CG1_02_55_41.
OC Archaea; Candidatus Micrarchaeota.
OX NCBI_TaxID=1805251 {ECO:0000313|EMBL:OIO26906.1, ECO:0000313|Proteomes:UP000183464};
RN [1] {ECO:0000313|EMBL:OIO26906.1, ECO:0000313|Proteomes:UP000183464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG1_02_55_41 {ECO:0000313|EMBL:OIO26906.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- FUNCTION: Stimulates transcription elongation. {ECO:0000256|HAMAP-
CC Rule:MF_00950}.
CC -!- SUBUNIT: Heterodimer composed of Spt4 and Spt5. Interacts with RNA
CC polymerase (RNAP). {ECO:0000256|HAMAP-Rule:MF_00950}.
CC -!- SIMILARITY: Belongs to the SPT5 family.
CC {ECO:0000256|ARBA:ARBA00006956}.
CC -!- SIMILARITY: Belongs to the archaeal Spt5 family. {ECO:0000256|HAMAP-
CC Rule:MF_00950}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIO26906.1}.
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DR EMBL; MNVI01000004; OIO26906.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4UQ00; -.
DR STRING; 1805251.AUJ15_00410; -.
DR Proteomes; UP000183464; Unassembled WGS sequence.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006354; P:DNA-templated transcription elongation; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR CDD; cd06091; KOW_NusG; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 3.30.70.940; NusG, N-terminal domain; 1.
DR HAMAP; MF_00950; Spt5_arch; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR005100; NGN-domain.
DR InterPro; IPR036735; NGN_dom_sf.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR011590; Spt5_arc.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR NCBIfam; TIGR00405; KOW_elon_Spt5; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF03439; Spt5-NGN; 1.
DR SMART; SM00739; KOW; 1.
DR SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:OIO26906.1};
KW Protein biosynthesis {ECO:0000313|EMBL:OIO26906.1};
KW Transcription {ECO:0000256|HAMAP-Rule:MF_00950};
KW Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00950}.
FT DOMAIN 92..119
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
SQ SEQUENCE 148 AA; 16352 MW; 5209432CC5F2D5C9 CRC64;
MLLAYRVTAG QESIVADMLY EKAKKTTKEG RNPIDALLVS ARLKGYLIVE THNATEAKQL
ITNVPHVKSV LSNEIPFEEI KGMLESKPQK IVLNKGDIIE VTSGPFKGER AKVSHVNEDK
EEITVELIEV AVPIPVTIKL NAVKIIPQ
//
