ID A0A1J4UWK3_9ARCH Unreviewed; 1699 AA.
AC A0A1J4UWK3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Chromosome segregation protein SMC {ECO:0008006|Google:ProtNLM};
GN ORFNames=AUJ14_01175 {ECO:0000313|EMBL:OIO26734.1};
OS Candidatus Micrarchaeota archaeon CG1_02_55_22.
OC Archaea; Candidatus Micrarchaeota.
OX NCBI_TaxID=1805250 {ECO:0000313|EMBL:OIO26734.1, ECO:0000313|Proteomes:UP000182370};
RN [1] {ECO:0000313|EMBL:OIO26734.1, ECO:0000313|Proteomes:UP000182370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG1_02_55_22 {ECO:0000313|EMBL:OIO26734.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIO26734.1}.
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DR EMBL; MNVH01000018; OIO26734.1; -; Genomic_DNA.
DR Proteomes; UP000182370; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR CDD; cd00081; Hint; 2.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 2.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR006142; INTEIN.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR004042; Intein_endonuc.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR004860; LAGLIDADG_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR NCBIfam; TIGR01443; intein_Cterm; 1.
DR NCBIfam; TIGR01445; intein_Nterm; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF14890; Intein_splicing; 1.
DR Pfam; PF14528; LAGLIDADG_3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PRINTS; PR00379; INTEIN.
DR SMART; SM00305; HintC; 1.
DR SMART; SM00306; HintN; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 3: Inferred from homology;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Protein splicing {ECO:0000256|ARBA:ARBA00023000}.
FT DOMAIN 275..412
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT DOMAIN 564..586
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
FT COILED 693..768
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 824..886
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 972..1006
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1199..1296
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1699 AA; 187949 MW; C105CF293AF062BC CRC64;
MHVSEIHLRN FKSFGSSKVK LSPGFNAIVG PNGSGKCLRG DSRILLTDGT RLSIKELVDG
ALSSSTDNQV LGDGILTLQN SSGAAVFSLN PLTGKIESSR VQAFVKRKSP ESLAEIVTRS
GRRIVTTTYH PLITIRDAEI AAVKAEDLRV GEFVALPRGL RLPESKINLP LELARRLTRL
YLGDSCVELR RLIAEKKLNS EKTWRQVSVD SGVIETELRG LASGQSIPLH SAFRLTQWLG
LSELEASKIL SRVKAKNQHI VTAIPLTLDC ALAKFLGYLI SEGRLVKNEA FFFNDSPEIR
DDFSASCKAA FGLSPTPCLN GKKTFLVLPS AAVAALLEHV FGMPPYSHSR DKRIPPQLLS
APLNSVMAFL SALYDGDGSV SQPGSSKVCV EYATASRALA DDLATLLLRF QIHSRISAGG
KFASNTVAKT RRTYYRVNIY GLEDAEKLSG AIHSSILKRP AILRVLEKHS GVKRGTAVDV
IPNSNGFINS ALRKAGYTSR RLKGEAPARI RAYFEDRCLP TRKGLVEVAT LVNKQHAAQL
SVLAESEVFW DEIAQIRAVP GEEWVYDLCV EGNHNFLAEG VFAHNSNIID ALVFAFGESS
LKSMRVKKST DLILSNNKVA EVSLHLTDGK ANSTVGRMVN RDGKTKYSMD GKRTKKYGIE
NFLTHHALSL TNVIKQGEVQ RIVEINSKER RHLIDVVANV AEYEDKKREA LNELARVEEH
LREASTVLGE REGYLRELEN ERSNALKYRE LKSELDAIKA TLASLEVASK TREFEALINA
DVDYQNKLEA LDAKVREIEA AILAKNGEKD EINKQIFARG QGAEADLQRE IDSLTNAVEN
ARNAIAEKQA QLAVLAKKIH EQKLDKQRAG DEVKGADKQK IDLEKELAET NLVLGEKRAG
YESIIGASDK FSQKFHESRA MVERAGDDML QAKQRLSELQ ASVSSSEEII RLKQKEIERL
KDGNTADYSP KLAQLSSEEK TSKVELANAQ KQLDALFERE KRLNEQVPVL EDLILAAREK
VVEISGRVRM AADSPASSSV EAVLALKEKT SGIYGTVEEL VSYPSKYAVP IQTALGPRAS
FVVVDSVKTA SKAIDFLKSK KLGRVSFIPL DKIRSSSISA EDRKHASGKG SHGFVLDHLE
YDAEHAAAIE FVCGSTIIME SLAEAEPIIG KIRLTTMDGE LVEGSGLISG GSFKVKVNLA
GERKQLEEWE RKHDVAKEEK DKLFADLTVL REETSEARKR KADAELALRS VEIQLSHLSE
QERSEAAKQS NVKGAVASLE SEIVEARKQI EAGDTERREL IRRLSELNLQ ILEAKQFLDV
EKEANYGNKV KELERAIGDL KVRVAEQDNS LKTAVTQYTL YSKQFDSASK ALAELEVEDA
ACREAVDAAD KTIKDSQVLL KVKLVEQKQL SGKFMDLINK REKLDGEIHK LANESGKMGF
EKEKLDRQKG DSRVRRAVIE EQLRNAKVAL EEHAGVAVIE GKTLEDKPEL LARSKILSGS
MGELGNVNLR AIELYDKRLA EYKDQQEKVQ RLFNEKEAVI GIITEIEGKK IATFMNTFNV
INENFKRVFS QIFQGDGHLF LENPEKPFDA GLTIEVKLSN KEVKYLELMS GGEKSLIALI
FLFAIQSVNP SGIYILDEAD AALDAENSRK LAQLVKVLSA DTQFIVVSHN QNVYKNADTL
VGVAMTREGS RLVEVKLTE
//
