ID A0A1J4X4Y8_9PROT Unreviewed; 246 AA.
AC A0A1J4X4Y8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=tRNA 2-thiocytidine(32) synthetase TtcA {ECO:0000313|EMBL:OIO54513.1};
GN ORFNames=AUJ55_11815 {ECO:0000313|EMBL:OIO54513.1};
OS Proteobacteria bacterium CG1_02_64_396.
OC Bacteria; Pseudomonadota.
OX NCBI_TaxID=1805333 {ECO:0000313|EMBL:OIO54513.1, ECO:0000313|Proteomes:UP000192865};
RN [1] {ECO:0000313|EMBL:OIO54513.1, ECO:0000313|Proteomes:UP000192865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG1_02_64_396 {ECO:0000313|EMBL:OIO54513.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIO54513.1}.
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DR EMBL; MNWR01000100; OIO54513.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4X4Y8; -.
DR STRING; 1805333.AUJ55_11815; -.
DR Proteomes; UP000192865; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd01993; Alpha_ANH_like_II; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR011063; TilS/TtcA_N.
DR InterPro; IPR035107; tRNA_thiolation_TtcA_Ctu1.
DR PANTHER; PTHR43686; SULFURTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR43686:SF1; TRNA-CYTIDINE(32) 2-SULFURTRANSFERASE; 1.
DR Pfam; PF01171; ATP_bind_3; 1.
DR PIRSF; PIRSF004976; ATPase_YdaO; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 21..188
FT /note="tRNA(Ile)-lysidine/2-thiocytidine synthase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01171"
SQ SEQUENCE 246 AA; 28007 MW; C17DA6963513254B CRC64;
MLKPVGEAIR RWNMIREGDR VLLGLSGGKD SMALLLVLRH LHRASPVRFE LGVANINPLT
DSYDPEPLHE IVQSLGLPFH MAREDLLTRA RKHIKNASYC SFCSRLKRGL LYQIARTQGY
NVLALAHHQD DIAQSFLMSA FYNGKLWTMA PNYAVREGDL RVIRPMALVR ERQNRAYVAE
AGIPVIEENC PACLMEERKE GEVELRMPTT REHIKALLAR EELEHPRLMD SLMTAMGPLL
DREGAE
//
