ID A0A1J4X789_9BACT Unreviewed; 430 AA.
AC A0A1J4X789;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 13.
DE RecName: Full=UDP-glucose/GDP-mannose dehydrogenase C-terminal domain-containing protein {ECO:0000259|SMART:SM00984};
GN ORFNames=AUJ46_03060 {ECO:0000313|EMBL:OIO54295.1};
OS Candidatus Peregrinibacteria bacterium CG1_02_54_53.
OC Bacteria; Candidatus Peregrinibacteria.
OX NCBI_TaxID=1805323 {ECO:0000313|EMBL:OIO54295.1, ECO:0000313|Proteomes:UP000183121};
RN [1] {ECO:0000313|EMBL:OIO54295.1, ECO:0000313|Proteomes:UP000183121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG1_02_54_53 {ECO:0000313|EMBL:OIO54295.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIO54295.1}.
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DR EMBL; MNWP01000020; OIO54295.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4X789; -.
DR STRING; 1805323.AUJ46_03060; -.
DR Proteomes; UP000183121; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 320..417
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 430 AA; 47053 MW; 3DC763268521B00F CRC64;
MEKPVICIVG LGYVGLPLTY IFAKNRYDVR GYDLNKERIA ELKAGRDRTG ELTEEQLKKV
TIRYSDDPAV IGEASVVILA IPTPVDECNN PDLEPVKSAS RTVGKHLKKG MIVVFESTVW
PGTTEEICGP ILEEESGLKC GVDFKLGYSP ERVNPGDKEH TIEKIKKIVS GQDAETLDML
ANLYGSVIEA GVHRATNIKV AEMAKAIENA QRDLNIAFIN EVALLCNKVG IETKDVLEAA
ATKWNFLPFV PGLVGGHCIG VDPYYLVEKA RQLGMETQVI TAGRALNDSM SRHVAEQVAA
SLFTPNKVEG RGCGDHPRVL VLGLTFKENV PDTRNSKSGD VVKHLAALGC AVEVHDPFVA
EDEVTQNGWK QGSLQSGPYD AVVLLVPHRE YMSNLADLTK ALKSEGLIYD LKSILPAEEL
RVKGFKYRSL
//
