ID A0A1J4YXX6_9PROT Unreviewed; 690 AA.
AC A0A1J4YXX6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=AUJ86_03095 {ECO:0000313|EMBL:OIO79082.1};
OS Hydrogenophilaceae bacterium CG1_02_62_390.
OC Bacteria; Pseudomonadota; Hydrogenophilia; Hydrogenophilales;
OC Hydrogenophilaceae.
OX NCBI_TaxID=1805218 {ECO:0000313|EMBL:OIO79082.1, ECO:0000313|Proteomes:UP000182441};
RN [1] {ECO:0000313|EMBL:OIO79082.1, ECO:0000313|Proteomes:UP000182441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG1_02_62_390 {ECO:0000313|EMBL:OIO79082.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIO79082.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MNXE01000018; OIO79082.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4YXX6; -.
DR STRING; 1805218.AUJ86_03095; -.
DR Proteomes; UP000182441; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:OIO79082.1};
KW Cilium {ECO:0000313|EMBL:OIO79082.1};
KW Flagellum {ECO:0000313|EMBL:OIO79082.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 40..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 65..89
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 109..132
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 201..223
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 243..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 690 AA; 73765 MW; 0EAA9A8ACA703ADD CRC64;
MATTALPGMQ WQKLAAPVLV IAILAMMILP LPAFLLDVLF TFNIALAMIV LLISLYTLKP
LEFSVFPTVL LITTLLRLSL NVASARIVLM EGHTGADAAG KVIEAFGHFL VGGNYAVGIV
VFVILVVINF VVITKGAGRI AEVSARFTLD AMPGKQMAID ADLNAGLIGE DEARKRRAEI
SEEADFYGSM DGASKFVRGD AVAGIIIMLI NLIGGLIVGM AQHGMGLADA ASRYTLLTIG
DGLVAQVPAL VISTAAGMVV SRVSSSSDLS EQLTSQLFGK PQALYLAAGI LTLMGIMPGM
PHVAFLLIGS LLGGGAYWLR QQQQQAADLA AAAVPAAAPA EAEEVGWNDV AQVDRLGLEV
GYRLVPLLDK GQDGELLRRI RGIRKKIAQD IGFLIPPVHI RDNLQLRPSA YRITMKGVTL
AEGEVQVGKY LAINPGRVFG NLPGQVATDP AYGLPAVWIQ TDLREQAQTL GYTVVDAGTV
VATHLSKLIN DHAPELLGRE ETQQLLDYIA KDNPKLVEDL TPKQLSLSTI QKVLQNLLEE
RVHIRDMRTI LEALSEQAGR SQDPDELTAA TRTALARAII HEIFGGVQEL QVMALAPGLE
NILVQALTNR GESGIGLEPG LAERMVRETV EAADRQSQAG RPVVLLVPPA IRTLLSRFLR
RAAPGLRVIA HNEVPEGKTI KVELTIGASA
//
