ID A0A1J4Z535_9BACT Unreviewed; 741 AA.
AC A0A1J4Z535;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=AUJ89_00810 {ECO:0000313|EMBL:OIO81396.1};
OS Candidatus Omnitrophica bacterium CG1_02_43_210.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1805286 {ECO:0000313|EMBL:OIO81396.1, ECO:0000313|Proteomes:UP000182209};
RN [1] {ECO:0000313|EMBL:OIO81396.1, ECO:0000313|Proteomes:UP000182209}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG1_02_43_210 {ECO:0000313|EMBL:OIO81396.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIO81396.1}.
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DR EMBL; MNXF01000005; OIO81396.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J4Z535; -.
DR STRING; 1805286.AUJ89_00810; -.
DR Proteomes; UP000182209; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 405..591
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 422..429
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 741 AA; 81537 MW; 54F880BCCE1AFE14 CRC64;
MPKLKRRQKN NTAEHLSPQK RNEVWGFIFL AVSILVFTAL ISYDQNDLSF YSSQPNTEIK
NLIGIIGAYI SGILVFLVGA TSFVIPFLTL SWSVSKFIGR QPQKLYVKTI GTVILFLSAS
SMLSLIATAE SVNSFKNGGL IGSFVSAHLA RYFGFPGTYI ILTTLVILSI LIATEFLVLP
FIASVFTFTI KAVSFLWQKI FSRIFSGKRQ KVVISTSKPK VRSIIKDPIT APPAPKPKVI
QIKPEALALA KQIDLKATRK QVSIDGYKLP ALDLLNSPPP LEERRIKDDL EKNSLILEET
LRDFGIEVRV AEVERGPVIT RYELEPAPGV KVNKIVALND DIALAMKAHS VRIVAPIPGK
ARVGIEVPNS SATLVYLQEV IATQEFQSQS KKYKLTMALG KDVSGAPMVT DLGDMPHFLI
AGTTGSGKTV CVNTIIMSLL FSNTPNDLRF VMVDPKMVEL AIFNGLPHLL CPVVTDHKKV
AATLNWVVEE MDARYRLLAS LGARNIELYN EKSPQKLPYL VVIIDELADL MMIAAAEIEN
AITRLAQLSR AVGIHIILAT QRPSVDVITG VIKANFPARI SFKVATKVDS RTVLDANGAD
KLLGKGDMLF LKPGAAKPIR GQCSLVSDAE IERLVNFIKA QTKPEYEESI INAQHKTNGS
GASGSSRIDK DLLYEDALNM VLETGQASVS MLQRRMRLSH IRAARIIDFM EQEGVVGPYQ
GSKAREILVP HKQLKEPEKV S
//
