ID A0A1J5CPG1_9BURK Unreviewed; 261 AA.
AC A0A1J5CPG1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=L-ornithine N(alpha)-acyltransferase {ECO:0000256|ARBA:ARBA00039866};
DE EC=2.3.2.30 {ECO:0000256|ARBA:ARBA00039058};
DE Flags: Fragment;
GN ORFNames=AUK50_01525 {ECO:0000313|EMBL:OIP21391.1};
OS Comamonadaceae bacterium CG2_30_57_122.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae.
OX NCBI_TaxID=1805089 {ECO:0000313|EMBL:OIP21391.1, ECO:0000313|Proteomes:UP000182154};
RN [1] {ECO:0000313|EMBL:OIP21391.1, ECO:0000313|Proteomes:UP000182154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG2_30_57_122 {ECO:0000313|EMBL:OIP21391.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3R)-hydroxyacyl-[ACP] + L-ornithine = a lyso-ornithine
CC lipid + H(+) + holo-[ACP]; Xref=Rhea:RHEA:20633, Rhea:RHEA-COMP:9685,
CC Rhea:RHEA-COMP:9945, ChEBI:CHEBI:15378, ChEBI:CHEBI:46911,
CC ChEBI:CHEBI:64479, ChEBI:CHEBI:78827, ChEBI:CHEBI:138482;
CC EC=2.3.2.30; Evidence={ECO:0000256|ARBA:ARBA00036203};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20634;
CC Evidence={ECO:0000256|ARBA:ARBA00036203};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. OlsB subfamily.
CC {ECO:0000256|ARBA:ARBA00038095}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIP21391.1}.
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DR EMBL; MNXW01000035; OIP21391.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J5CPG1; -.
DR Proteomes; UP000182154; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR PANTHER; PTHR37323; GCN5-RELATED N-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR37323:SF1; L-ORNITHINE N(ALPHA)-ACYLTRANSFERASE; 1.
DR Pfam; PF13444; Acetyltransf_5; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:OIP21391.1};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OIP21391.1}.
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 261
FT /evidence="ECO:0000313|EMBL:OIP21391.1"
SQ SEQUENCE 261 AA; 29020 MW; A3DC076406C29D82 CRC64;
MRELPNPTFD LSPTSLPRGL LHRPSPTSQP VQGLAASPTK DRALVVTWAR HLDQVRQVQR
LRYKVFAEEM GARLSSAVPG HDIDLFDNFC EHLMVCDQVT DEVVGTYRLL TPAQAKRAGG
MYSDQEFDLT RLRSLREHMV ELGRSCVHPD YRHGGVIMAL WGALAEFMVR NKLDTMIGCA
SIPMLHNGVT SGDAAASIWQ QVKQTHMAGI EYHVRARLPL PVEQFDTSLV VEPPALIKGY
LRLGAKVLGA PAWDPDFNTA D
//
