ID A0A1J5F1I6_9BACT Unreviewed; 770 AA.
AC A0A1J5F1I6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AUK10_01485 {ECO:0000313|EMBL:OIP54113.1};
OS Candidatus Gracilibacteria bacterium CG2_30_37_12.
OC Bacteria; Candidatus Gracilibacteria.
OX NCBI_TaxID=1805211 {ECO:0000313|EMBL:OIP54113.1, ECO:0000313|Proteomes:UP000182482};
RN [1] {ECO:0000313|EMBL:OIP54113.1, ECO:0000313|Proteomes:UP000182482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG2_30_37_12 {ECO:0000313|EMBL:OIP54113.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIP54113.1}.
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DR EMBL; MNYO01000048; OIP54113.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J5F1I6; -.
DR Proteomes; UP000182482; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 199..340
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 383..756
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 770 AA; 86084 MW; 4B6A42A60CECBF9F CRC64;
MQKKLIHLIN FLIIQFSHID RVRMVFFGFI LFAILIIWTT FKYTVLEYTY YKSLADKQQV
VTVKNPVSRG TISSNNEPAG VFATSTDLSD LAIDPKEIGS KEKLEVFLAD LIYEELCSKL
PEEHCMDNIL DYLKQDEEGD LIMNDIVIKN KIREEIHQKI AKEFIDSVIV KENLSKKEIS
ELEPLTTGTD SSFSIINNSL YVDPTKIENK DEMTTKLMGI LALSKNELDF KLSNRTTRYI
KIIRKMGLST RDMIDNRIQA EKINIAQGRM LDSESIYHFF ILEANPTRFY PEKNMGGQIV
GFVDNANEGK YGIEGYFNEE LKGKEGARIA KKDISGRTIG SFDLGEKKMV NGTDIKLTID
RNIQKEVTKI LADGVKEFRA NKGSVVIMDP KTGAIIAMVT YPDFDPNNFG EVYEIEKVSY
AKYPIPSFDL LGVPLFIEDS EKGSPTMVAK KKISLRAATE AEIDNRAIPK YKYKNMFGPG
TYEADPVSAL YEPGSVFKAV TVAIAIDTGD IKPSDTYTDK GYAEIDQYKI KNVSNECIGL
HTYAHALDWS CNVGMIDIVQ KIGKSLFYKY INDFGFGQKS NITLEGETFR KIDPYEKWSR
AKLFTMAFGQ GITATVLQMA TAYSTLANGG IYMQPYIVDS LTLADGTVVK NTPNPLRRVI
KEDTSKKIIA MLTEGAKIGF AKKGGVDGYD VAGKTGTSQI AAKGAYEIGE AGHTITSYGG
FAPASNPKFV MIVKIERPRT AQYSETTSSA VFSKIAKYLF NYYGIPSNTK
//
