ID A0A1J5FL72_9BACT Unreviewed; 1363 AA.
AC A0A1J5FL72;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AUK34_05555 {ECO:0000313|EMBL:OIP60972.1};
OS Ignavibacteria bacterium CG2_30_36_16.
OC Bacteria; Ignavibacteriota; Ignavibacteria.
OX NCBI_TaxID=1805221 {ECO:0000313|EMBL:OIP60972.1, ECO:0000313|Proteomes:UP000183261};
RN [1] {ECO:0000313|EMBL:OIP60972.1, ECO:0000313|Proteomes:UP000183261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG2_30_36_16 {ECO:0000313|EMBL:OIP60972.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIP60972.1}.
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DR EMBL; MNYQ01000089; OIP60972.1; -; Genomic_DNA.
DR STRING; 1805221.AUK34_05555; -.
DR Proteomes; UP000183261; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 3.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 787..808
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 840..1064
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1111..1226
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1258..1357
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1159
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1363 AA; 155789 MW; FA86992A3DA0DFA3 CRC64;
MIIMRFLFKI FTVLLIGLIF YPINIFGQSD EFSGYEFESF TVQDGLSSDI VYSLLQDKEG
YIYVGTSTGL DRYDGIRFSK MPILSTTTTH KQNPIRCLAE DEEENIWIGS RLSGLIKYDK
KNKYFTHFNQ NPYQNSISDN FIWAVICDTG NIIYAATRSG VDKFDTKKEL FSKLENESSV
SGIFRFIKDD KNRIWARSSK GVLILYPKLM KLRLVDFSNL NMNLNSLGTI IEEPGSEGRV
FWISANNLFV RIDIKSRETD KFDLLKLDPN LDKGRITNFL FDKNGDLWIG SRDGLGILKK
NKNNFNYIPL VNNKFKAPGF SGNTISGILQ DKAGVIWVST ENGGINKYEQ RKIVVSPFDD
SISKRYRDIL SVQLVANKLY LGVKQGLLEY DLTSKEQKVY DNLNSSPKKY SIRLTDIYQQ
PSDPNILWIA SAEEGIHRFN IKTKLLEKFW RREMIKVLSY DCVMEDDNQN IWFGTTSSGI
YKYFPKSDSI YSFSNNANKS APKGGITVLY NTKKGGIWIG TDGDGLHKYN SLKDDFINDI
LSRKDSTLKN LIINAIKEDA NDNLWIGTSR GLVKLNVLTN EFKLYPLESK SRKAAVLSLE
FDSSGNLWVS SMYNICRFDI RREMFSVYSP DKGQNTNYLP NCSQVLPDGK ILFGGYWNIS
YIDPGQLNSH RPEIVITQIK LADQEPMIDP VLKDHFLVSL SYDENYFSIE FNALSFASPG
RNKFIYMLEG YDKEWIESGM DRIARYTNVE PGEYIFEVKG SNCDGVWNEK GASFAVTILP
PFYKTTWAYL FYVILLILFI YGIVKFFLYR DRLQNEAILK RKEAEQLQQL DQIKSRFFAN
ISHELRTPLT LIIGPLESLI SKEKGNGNFQ LMYNQAKKLL NMINQLLDIS RLESGKMRLK
ISKRDIIQHS QALISSFHPL AAKRKIKLSL ISPHTELKTY YDADKYEKIL INLLSNAFKF
SPNEDEIIVT IESSNLTEFK GQPFPEGYIQ ITVKDNGSGI PETSAEKIFE RFYQLENQNV
KKFGGTGLGL SIVKDFVELH GGLIYINTKV EKGAEFNFIL PLGKSTFKDA EFEQYFEESE
SQTSTETLQN TVEIEITEPE KEISSNDAAK IILVIEDHEE VNDYIKNILS KYYKVIQSYD
GESGLSAALK TVPDLIVSDI MMPGIDGYEV CKQLKTDEIT SHIPVILLTA KASLDSKIEG
LETGADDYIT KPFSEEELKL RIKNLIATRE KLREKFAGQL NLNPTELSVT SADEKFLNRV
KEVVEKNLPN PDFNVEDFSG KVGMSRMTLH RKLKAVTGLS AKELIQEMRL RRAAQLLEKN
IGTIAEVAYE VGFKEPSYFT KCFQKRFNVL PSEYVKHEIS PII
//
