ID A0A1J5FQE5_9BACT Unreviewed; 790 AA.
AC A0A1J5FQE5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=AUK19_01510 {ECO:0000313|EMBL:OIP59722.1};
OS Candidatus Moranbacteria bacterium CG2_30_45_14.
OC Bacteria; Candidatus Moranbacteria.
OX NCBI_TaxID=1805255 {ECO:0000313|EMBL:OIP59722.1, ECO:0000313|Proteomes:UP000183500};
RN [1] {ECO:0000313|EMBL:OIP59722.1, ECO:0000313|Proteomes:UP000183500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG2_30_45_14 {ECO:0000313|EMBL:OIP59722.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIP59722.1}.
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DR EMBL; MNYT01000020; OIP59722.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J5FQE5; -.
DR STRING; 1805255.AUK19_01510; -.
DR Proteomes; UP000183500; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 409..615
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 764..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 426..433
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 790 AA; 87197 MW; 6BED897F4E943296 CRC64;
MGRKKKVPAE PEDDGFKFED ILHSDAKRSI VAVFLFALSL LFLLAYFNTA GVLGEWLDTG
LGTLFGWGKW LFPLLLIIAG ILFLKRRTTT LADAVRFIGL AFAFFSVLGL FHLYSGEGTK
EFLQIARSGQ GGGYIGFCFA YILANFTGKV AGTIILIALF AIGIIASFNV SLIHSFEQLQ
GKLRPKEKEA SSLDEEETVT PIITEEKIDT IPTEKGVSET PPFGENMDLA ANNIRHIEFK
EDDGASENNA NEDDTVLVPA FVRPKKVQHR RGHVQRELPS VDLLESTMGQ AVGGDTEQKK
HIIQSTLKYF GIEVEPGEAL VGPTVTRYTF SPAFGVKLSR ITALSDNLAL ALSAKSIRIE
APIPGQALIG IEVPNNTVAT VRLKAIIESE DFRERKSDLM LVLGQDVAGK HILADLRKMP
HLLIAGRTGS GKSVCINTFL ISLLYQNSPE DLKLILVDPK RVELSIYKGI PHLQTDVIVD
MKKVVNALRW AVGEMEHRYK VLEEVHARDI VAYRERALLG EHKTVIDAET GKVVKEPFLN
LPYFVIVIDE MADLMSMHGK EVEALINRLA AKSRAIGIHL LLATQRPEVT VITGLIKSNI
PTRIAFQLKS QIDSRTILAA GGAEKLLGNG DMLYSPSEGT EMRRIQGAFV SDDEVKRVTT
FWRNQKENFG EEGIGGELDL DDKTVDITEA MDELDNGSKE DALYEQAKEM TIRTGRASTT
SFQTAFSVGY PRAARLMHLL EENGVVGMIG GKKTVLMNEG KVIPASAEDE KEQYGDNPLA
DQSDRDKWQL
//
