ID A0A1J5HN25_9BACT Unreviewed; 509 AA.
AC A0A1J5HN25;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Ribonucleotide reductase large subunit C-terminal domain-containing protein {ECO:0000259|Pfam:PF02867};
GN ORFNames=AUK45_01120 {ECO:0000313|EMBL:OIP81438.1};
OS Candidatus Peregrinibacteria bacterium CG2_30_44_17.
OC Bacteria; Candidatus Peregrinibacteria.
OX NCBI_TaxID=1805324 {ECO:0000313|EMBL:OIP81438.1, ECO:0000313|Proteomes:UP000183123};
RN [1] {ECO:0000313|EMBL:OIP81438.1, ECO:0000313|Proteomes:UP000183123}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG2_30_44_17 {ECO:0000313|EMBL:OIP81438.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- COFACTOR:
CC Name=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408;
CC Evidence={ECO:0000256|ARBA:ARBA00001922};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIP81438.1}.
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DR EMBL; MNZJ01000012; OIP81438.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J5HN25; -.
DR STRING; 1805324.AUK45_01120; -.
DR Proteomes; UP000183123; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.20.70.20; -; 2.
DR InterPro; IPR000788; RNR_lg_C.
DR PANTHER; PTHR43371:SF1; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR43371; VITAMIN B12-DEPENDENT RIBONUCLEOTIDE REDUCTASE; 1.
DR Pfam; PF02867; Ribonuc_red_lgC; 1.
DR PRINTS; PR01183; RIBORDTASEM1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
PE 4: Predicted;
KW Cobalamin {ECO:0000256|ARBA:ARBA00022628};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 123..444
FT /note="Ribonucleotide reductase large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02867"
SQ SEQUENCE 509 AA; 55542 MW; 4310B6EA8852E1FA CRC64;
MAFNALGMHR SDVLVTGRIL LPGEQPDELL DRIVDTFFAP EVQFGTQSAV VHRLKADFRD
LIMSGACIPG TPGMTNAGRQ LPLSSCAVAP TLDLTQDGSL DIVRAYYQKN MGLGFNLSGY
NDPVGHLLAL NKFCDKETQT GQYQRYIGNM AMLSCFHPHV LRFIRAKKEH PEITYFNLSV
DVTEAFMEAA LSGTDITLSD GTLVNASDIL DEIATSAWET GDPGIVFLDR MNRDNPVSHL
PYTSVPTCCE TGMVPGETNQ LGYINVAHFL TGSTYNYGGL TSAVKLMTRA LDNAVQASLN
HFPHAESRDV AQSKRRLGIG ICGLSDLLIL MGLNYDSDES RSVARDILSA INFGSKEASF
ELASSRGSCG AMEGHNAYTD GRYLEDKFGL HPTAVISADD WTLLAESIRQ RRQLRNILTT
TLPPTGRSSL LLGVSPSLEP ALKTAHEVPS RGHLLMMRDL VGTDTGVFDE SASKTVNMPR
AATVSDVREV FVDSYKLGLK NICVYRKTN
//
