ID A0A1J5IK24_9GAMM Unreviewed; 545 AA.
AC A0A1J5IK24;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=AUK56_08140 {ECO:0000313|EMBL:OIP94762.1};
OS Thiomicrospira sp. CG2_30_44_34.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Thiomicrospira.
OX NCBI_TaxID=1805397 {ECO:0000313|EMBL:OIP94762.1, ECO:0000313|Proteomes:UP000182935};
RN [1] {ECO:0000313|EMBL:OIP94762.1, ECO:0000313|Proteomes:UP000182935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG2_30_44_34 {ECO:0000313|EMBL:OIP94762.1};
RX PubMed=27112493;
RA Probst A.J., Castelle C.J., Singh A., Brown C.T., Anantharaman K.,
RA Sharon I., Hug L.A., Burstein D., Emerson J.B., Thomas B.C., Banfield J.F.;
RT "Genomic resolution of a cold subsurface aquifer community provides
RT metabolic insights for novel microbes adapted to high CO concentrations.";
RL Environ. Microbiol. 0:0-0(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIP94762.1}.
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DR EMBL; MNZS01000054; OIP94762.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J5IK24; -.
DR STRING; 1805397.AUK56_08140; -.
DR Proteomes; UP000182935; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..545
FT /note="diguanylate cyclase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012498481"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 418..545
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 545 AA; 61933 MW; A4A1CFA6EBAD3DC0 CRC64;
MRNSNYFSIY KALLFTGLFI CLVFASRANA QPLNIDWQLL SFDESQQFNP EQPESHNTLQ
KVDGISLVGG HYLYSGTLTI EKDDFYVIDF KNTSTIDQFS FYLYDQQNKL IDQASGGIGS
REPDPFFLRH GRSFHLKAGQ YQVLAEIASP YFIAQPVPYV SKLADYQQEI KLGNAVVLIG
IGIFLSMGIY YGALSFARSR NTEILYALFI FSNLLFNAGT HQILSQLFDW HNFYLISFPI
LISNFIYVFF VMKLLDINPV NHQKLHTYGI VSLVFLAIFA LFALMSPNWI NEMARYGVWV
FLLYGLVVGM TLSFQGRIVA RLYLISLMSF IIFASMATIP TQLSSNTLFV EHYGLASVAM
EVILLALVMT YQVGELYRER MNMLLSLDHN KKLAHTDSLT QIPNRYALEV ELDSSVVKEA
SLTYIDMDNL KLYNDRFGHA KGDEMLSVFA NLMKQGMEGH GNIYRLGGDE FAVTCPAGNT
HFVKTLIDNV IHKMRETGFE NSGASSGTAF MYEVESTSDL KLLADMRMYE NKQRRKTENV
NPSQV
//
