ID A0A1J5LKD2_9PROT Unreviewed; 503 AA.
AC A0A1J5LKD2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase {ECO:0000313|EMBL:OIQ31411.1};
GN ORFNames=BM562_07520 {ECO:0000313|EMBL:OIQ31411.1};
OS Alphaproteobacteria bacterium MedPE-SWcel.
OC Bacteria; Pseudomonadota; Alphaproteobacteria.
OX NCBI_TaxID=1860092 {ECO:0000313|EMBL:OIQ31411.1, ECO:0000313|Proteomes:UP000183546};
RN [1] {ECO:0000313|EMBL:OIQ31411.1, ECO:0000313|Proteomes:UP000183546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MedPE-SWcel {ECO:0000313|EMBL:OIQ31411.1};
RX PubMed=27446036; DOI=10.3389/fmicb.2016.00996;
RA Lopez-Perez M., Kimes N.E., Haro-Moreno J.M., Rodriguez-Valera F.;
RT "Not All Particles Are Equal: The Selective Enrichment of Particle-
RT Associated Bacteria from the Mediterranean Sea.";
RL Front. Microbiol. 7:996-996(2016).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIQ31411.1}.
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DR EMBL; MPDC01000009; OIQ31411.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J5LKD2; -.
DR STRING; 1860092.BM562_07520; -.
DR Proteomes; UP000183546; Unassembled WGS sequence.
DR GO; GO:0018480; F:5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity; IEA:InterPro.
DR GO; GO:1901023; P:4-hydroxyphenylacetate catabolic process; IEA:InterPro.
DR CDD; cd07093; ALDH_F8_HMSADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR011985; DH_HpaE.
DR NCBIfam; TIGR02299; HpaE; 1.
DR PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43720:SF2; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 36..489
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 266
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 503 AA; 54535 MW; 64B5E6172DD1E87B CRC64;
MSDLASNLAK LAPLLDRHKV NGITNLIGGK SCPSATGRTF DTLSPVDESV ICAVARSEST
DIDAAAKAAK EAFPAWRDTP AADRQAILHR IADAIVERAE DIALCECWDT GQALRFMSKA
ALRGADNFRF FGDRALTARD GQMLPSPTLM NVTTRVPIGP VGIITPWNTP FMLSTWKIAP
ALAAGCTIVH KPAEFSPLTA RLLAEIAHDA GLPAGVWNLV NGYGEEAGKA LTEHPDIKAI
AFVGESRTGS MIMAQGAPTL KRAHFELGGK NPVVVFDDAD LDRALDAAIF MIYSLNGERC
TSSSRLLIQE SVADRFEAKL IDRVKKIRVG HPLDPATEVG PLIHKVHFDK VTSYFDTALR
EGATIAAGGP RHGDRGWFVT PTLFTDASND MAIAQEEIFG PVLTMIRFKD EEDALAKAND
TPYGLTGYIW TNDITRAMRF SHQLEAGMIW VNSENVRHLP TPFGGVKASG IGRDGGDWSF
DFYMEQKHIG FATGQHKIPR LGA
//
