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Database: UniProt
Entry: A0A1J5TZ31_9GAMM
LinkDB: A0A1J5TZ31_9GAMM
Original site: A0A1J5TZ31_9GAMM 
ID   A0A1J5TZ31_9GAMM        Unreviewed;       432 AA.
AC   A0A1J5TZ31;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   16-JAN-2019, entry version 16.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=BGC33_13455 {ECO:0000313|EMBL:OIR25468.1};
OS   Bathymodiolus thermophilus thioautotrophic gill symbiont.
OC   Bacteria; Proteobacteria; Gammaproteobacteria;
OC   sulfur-oxidizing symbionts.
OX   NCBI_TaxID=2360 {ECO:0000313|EMBL:OIR25468.1};
RN   [1] {ECO:0000313|EMBL:OIR25468.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BAT/CrabSpa'14 {ECO:0000313|EMBL:OIR25468.1};
RX   PubMed=28878861; DOI=.1186/s40793-017-0266-y;
RA   Ponnudurai R., Sayavedra L., Kleiner M., Heiden S.E., Thurmer A.,
RA   Felbeck H., Schluter R., Sievert S.M., Daniel R., Schweder T.,
RA   Markert S.;
RT   "Genome sequence of the sulfur-oxidizing Bathymodiolus thermophilus
RT   gill endosymbiont.";
RL   Stand. Genomic Sci. 12:50-50(2017).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OIR25468.1}.
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DR   EMBL; MIQH01000322; OIR25468.1; -; Genomic_DNA.
DR   RefSeq; WP_071563469.1; NZ_MIQH01000322.1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      123    253       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      339    408       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     131    138       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   432 AA;  48817 MW;  4A9D98EE33CB49AE CRC64;
     MPTTWEKCLE TLKDTIPVGQ FSVWIQPLKA TEKGNILTIV APNTSTVDYL KTNLKQKIKD
     AVARHNKDLK INIGTEIQQA KKNTKHSTPL FPEYTFDNLV MGNANQIAYG AIRQIAEDLK
     KSPYNPCIIY GDSGLGKTHL MQAAGHLVKQ QNPKTKIIYA PVMDFVRNIT TSLRHKTIEN
     IKSYYQSADL LLVDDIHLIA GKEKSQEEFF HIFNFLFTTK KQIIFTCDQP PTNIKSLENR
     LKTRFAQGLN LSLTPPELEM RAAILLKKSE SPAINITFSA DIALYIASNI TSNVRDLEGA
     LLKLKAFVDF SKLDDHIITK EIIDIALGDL IKPKAKNIDI NDIQKESAKH YGVTISDLSS
     KNRKQSIVLA RQMAIFIAHE MTSLSLSKIG KHFGNRDHST VLHAIKRIKE RTEKEPEIKD
     EYELLKLKLA NL
//
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