ID   A0A1J5WZB3_9MICR        Unreviewed;       590 AA.
AC   A0A1J5WZB3;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Mechanosensitive ion channel protein {ECO:0000313|EMBL:OIR58982.1};
GN   ORFNames=A8A55_0244 {ECO:0000313|EMBL:OIR58982.1};
OS   Amphiamblys sp. WSBS2006.
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Amphiacanthidae;
OC   Amphiamblys.
OX   NCBI_TaxID=1866961 {ECO:0000313|EMBL:OIR58982.1, ECO:0000313|Proteomes:UP000182028};
RN   [1] {ECO:0000313|EMBL:OIR58982.1, ECO:0000313|Proteomes:UP000182028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSBS2006 {ECO:0000313|EMBL:OIR58982.1};
RX   PubMed=27694476;
RA   Mikhailov K.V., Simdyanov T.G., Aleoshin V.V.;
RT   "Genomic survey of a hyperparasitic microsporidian Amphiamblys sp.
RT   (Metchnikovellidae).";
RL   Genome Biol. Evol. 0:0-0(2016).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OIR58982.1}.
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DR   EMBL; MKPU01000005; OIR58982.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J5WZB3; -.
DR   VEuPathDB; MicrosporidiaDB:A8A55_0244; -.
DR   Proteomes; UP000182028; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR016688; MscS-like_plants/fungi.
DR   PANTHER; PTHR31618:SF7; MECHANOSENSITIVE ION CHANNEL PROTEIN; 1.
DR   PANTHER; PTHR31618; MECHANOSENSITIVE ION CHANNEL PROTEIN 5; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000182028};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        113..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        165..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..48
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..66
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   590 AA;  66308 MW;  500D7ACB9FED0FCE CRC64;
     MNTETAFSPA EKTRMENSSS ERETPTLSSS EALTQEKRPN NTPPQENGKP DSPVKRSESR
     LYADEPAKRS KAQTDFLETT LLLLAVFIMC AFPAALLRLS VAAGKRKEWH NTAMYLGTLG
     CAVVSVFYVL YVFFLLFPDF LVEMASLIET QNETVHRMAV RVKSLALLLS LSAAASIIAV
     FFFTEDAWFR RLFEKMKLPY VKETVFGTNL DSIPVYLHEL SFFTALLAAT KYLLDLYQEK
     NNNKTYEKRI AKSNGTGRTL RALLFGETAE KTTLESAKKR MGFELEDDDL LNISGEKDAR
     ALANSIFRKL AERGKDAIYP HDIEYLFPEE KNEIVGAMGG RHTGCVSLKM LRKYIVSYYK
     ERTNLKKSLR NHTRMYKKFT AVVFAIVLVI SALLFKSTNI GGKVDVYKSA FSVGMVATLG
     FVFAEIPQDM FKTLTFTFVL HPFDCGDYIT FGGKDYIVDQ ITILTVKMTD VLSSATCYLS
     TKSLVGKDFL NHSRSGEYIE HVSVLVQPVN QAAPEELKKA VQDCIKKDAS DFTGFVSLEN
     VEFQKNTMRI SLAVEHTDNI GIRGEACERK TRLGTHVQES LEKTGLVLAE
//