ID A0A1J6HU19_NICAT Unreviewed; 1030 AA.
AC A0A1J6HU19;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN Name=PUB42 {ECO:0000313|EMBL:OIS95835.1};
GN ORFNames=A4A49_19419 {ECO:0000313|EMBL:OIS95835.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIS95835.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIS95835.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIS95835.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIS95835.1}.
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DR EMBL; MJEQ01037194; OIS95835.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J6HU19; -.
DR STRING; 49451.A0A1J6HU19; -.
DR EnsemblPlants; OIS95835; OIS95835; A4A49_19419.
DR Gramene; OIS95835; OIS95835; A4A49_19419.
DR OMA; WTMRNEA; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000187609; Chromosome 12.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45958; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR PANTHER; PTHR45958:SF4; U-BOX DOMAIN-CONTAINING PROTEIN 42-RELATED; 1.
DR Pfam; PF00514; Arm; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 5.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 241..319
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 364..401
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1030 AA; 115427 MW; 56A70B82F690717C CRC64;
MSHFLLQING ERDRVGILAE SLLENISEFT KSVVSIDVEK ENFIEIGSYL YRASALIMEL
QIGTNTTSNV IDKLQSMLGS VHLANELIKK GQNYRQKNQL IEPSIVIEQL HVVNRHVAEG
LSLIPSSFYG EQECAEIAAK SLSKDMKSAA FVARKILVSD QKELEVHMFT SREFLTNETA
ERDTETDLYS INIDVSMENI RLADSTNIYI SDNSRSSISR SLHLQNHGNC SARSESEYME
PLYETFFCPL TKKIMEDPVT IESGVTYEKE AISEWINKFD NHEEISCPKS GQKLKSRNLS
TNVALKATID EWKERNETAR IKAARAALSS ASSTQDIILK AIEDLQIICL RKPYNKVQVL
SIGIIPLLGN LLDNRSRSIR CATLELLRHL AEDDDEELIA QIIDISTVTR MLSSNHRPIR
HASLSLLLEV SKSQFLCDNI GEVPGAILML ITAKYRHSDD AFVADKADEV LKSLEKYPCN
IKHMAENGYL EPLLYHLIEG SEEMKMEMAR YLGEIVLGLD SITYVAEKAS PSLIKMVESG
NSLSRNAAFG ALQQISSHHS NANTLVESGL VQIMVEEIFT QAIHDEQINS KKEAAGILAN
VLESGLELEN LQVNGRGHTL ASDYMIFNFI QRIKNSTPEE MNFHLVRILI CLMKYPKASS
TIISVIKETD ASYNLIELIN NPNEELSIVA LKLLIAFSPF MGHTISDRLC KTKGQPESLI
HAPPGSPRVT EKQAVSATLL AKLPHQNMTL NLALVNKNTI PAIIEQINKI HVSGTRTSRY
TSAYFDGLVG ILVRLTTILY DHQILHVVRT FNFTYIFTEL LVKTSSDEVK KLSAIGLGNL
SKQSVNLSKP PPIKNNKYIK SFLLRRCMSL HSKTQKVPLC PVHRGVCSAE DSFCLIDAKA
IERLLSCLHH ENVEVVEAAL SAISTLLDDK VDMDKSVNLL IEMQTIQHVL NVVKEHREDV
LWHKSFWLIE KFLSKGGDKS ASDISQDRLF PATVVSAFQH GDICTRQMAE KILMHLNKMP
YFANTASFTT
//
