ID A0A1J6HWK1_NICAT Unreviewed; 259 AA.
AC A0A1J6HWK1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Defective in cullin neddylation protein {ECO:0000256|RuleBase:RU410713};
GN ORFNames=A4A49_04405 {ECO:0000313|EMBL:OIS96769.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIS96769.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIS96769.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIS96769.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Neddylation of cullins play an essential role in the
CC regulation of SCF-type complexes activity.
CC {ECO:0000256|RuleBase:RU410713}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIS96769.1}.
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DR EMBL; MJEQ01037193; OIS96769.1; -; Genomic_DNA.
DR RefSeq; XP_019255588.1; XM_019400043.1.
DR AlphaFoldDB; A0A1J6HWK1; -.
DR STRING; 49451.A0A1J6HWK1; -.
DR EnsemblPlants; OIS96769; OIS96769; A4A49_04405.
DR GeneID; 109234172; -.
DR Gramene; OIS96769; OIS96769; A4A49_04405.
DR KEGG; nau:109234172; -.
DR OMA; NPDAYYK; -.
DR OrthoDB; 169757at2759; -.
DR Proteomes; UP000187609; Chromosome 11.
DR CDD; cd14350; UBA_DCNL; 1.
DR Gene3D; 1.10.238.200; Cullin, PONY binding domain; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR014764; DCN-prot.
DR InterPro; IPR042460; DCN1-like_PONY.
DR InterPro; IPR005176; PONY_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12281:SF2; DEFECTIVE IN CULLIN NEDDYLATION PROTEIN; 1.
DR PANTHER; PTHR12281; RP42 RELATED; 1.
DR Pfam; PF03556; Cullin_binding; 1.
DR Pfam; PF14555; UBA_4; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51229; DCUN1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 54..242
FT /note="DCUN1"
FT /evidence="ECO:0000259|PROSITE:PS51229"
SQ SEQUENCE 259 AA; 29962 MW; 9AE2264B98D07932 CRC64;
MNKLGIGRRD KVQQFMTITG ASEKVALQAL KASDWNLEGA FDIFYSQSQV KSSADTRRLE
ELYNRYKDPY SDMILADGIS LLCNDIQVDP QDIVMLVLSW HMKAATMCEF SKQEFIGGLQ
SLGIDSLEKL REKLPFMRSE MRDEHKFREI YNFAFSWAKE KGQKSLALDT AIGMWQLLFA
EKQWPLVDHW CQFLQARHNK AISRDTWAQL LEFARSVDPA LSNYDAEGAW PYLIDEFVEY
LTENGVVQKG QISDWSQKC
//
