ID A0A1J6HYJ1_NICAT Unreviewed; 799 AA.
AC A0A1J6HYJ1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Subtilisin-like protease sbt1.5 {ECO:0000313|EMBL:OIS97932.1};
GN Name=SBT1.5_2 {ECO:0000313|EMBL:OIS97932.1};
GN ORFNames=A4A49_01652 {ECO:0000313|EMBL:OIS97932.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIS97932.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIS97932.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIS97932.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIS97932.1}.
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DR EMBL; MJEQ01037192; OIS97932.1; -; Genomic_DNA.
DR RefSeq; XP_019254617.1; XM_019399072.1.
DR AlphaFoldDB; A0A1J6HYJ1; -.
DR EnsemblPlants; OIS97932; OIS97932; A4A49_01652.
DR GeneID; 109233263; -.
DR Gramene; OIS97932; OIS97932; A4A49_01652.
DR KEGG; nau:109233263; -.
DR OMA; SGRDIKQ; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000187609; Chromosome 10.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF618; SUBTILISIN-LIKE PROTEASE; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..799
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012046336"
FT DOMAIN 33..124
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 151..611
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 391..488
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 688..793
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 160
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 234
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 574
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 799 AA; 85157 MW; 2B0E1760751F88FB CRC64;
MGRCHSLQAA LFLTCSLFLT LIDANIISGN KQSYIIRVQN DMKPSAFSDV EHWYGSTLRS
LSSNPLNSAK SNSIQVETTD LEFLHVYKTV FHGFSARLTE KEAQELASRR GVLSVLPDRL
RQLHTTRSPH FLGLDSSASA PANLVSESDS GSNVVIGVLD TGIWPERLSF HDKGMGPIPS
FWKGECTQGQ DFTKANCNKK IIGARYFTAG YEARIGKIMN SSTDIKSARD SDGHGTHTAS
TAAGRAVEDA SLLGFAKGVA VGIAPKARIA AYKVCWKRGC MDSDILAAFD KAVDDGVNVI
SISIGGGAVP YNLDPIAIGS FGAMEKGILV SASAGNEGPR QMTVTNVAPW ITTVGASTID
RKFPADLVLG NGKRITGASL YSGDPLPDKQ LPLVYGGNVS VGIRNGARHS SSFSAATCMP
DSLDKERVRG KIVVCDRGGT PRVAKGEVVN EAGGAGVIVA NVAPMGEGLI ADAHLIPGLG
VTESAGNIIR DYINSNNNPT ATMAFYGTQL GVKPAPVVAS FSSRGPNAES IFVLKPDVIA
PGVNILAAWP DGVAPTELSS DTRRTQFNIE SGTSMSCPHV SGLAALLKGA HPDWSPAMIR
SALMTTAYTQ DQQGKMLLDE KSYNVSTVLD MGAGHVDPEK AVDPGLVYDI TVDDYLNFLC
ASNYSGRDIK QIARRPWRCM GKHHKPWDFN YPAISVVIDS TEAAGMGIVQ VTRTVTHIGE
APSTYTVLVT NPKGATVTVT PTKIDFREMG QRQSYVVRIK AENLAVTTLS SLVEVGMLNW
SDGKHQVVSP LVVVWKQGL
//
