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Database: UniProt
Entry: A0A1J6IKN0_NICAT
LinkDB: A0A1J6IKN0_NICAT
Original site: A0A1J6IKN0_NICAT 
ID   A0A1J6IKN0_NICAT        Unreviewed;       399 AA.
AC   A0A1J6IKN0;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   16-OCT-2019, entry version 13.
DE   RecName: Full=Arogenate dehydratase {ECO:0000256|RuleBase:RU363004};
DE            EC=4.2.1.91 {ECO:0000256|RuleBase:RU363004};
GN   Name=ADT1 {ECO:0000313|EMBL:OIT05685.1};
GN   ORFNames=A4A49_01653 {ECO:0000313|EMBL:OIT05685.1};
OS   Nicotiana attenuata (Coyote tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; asterids; lamiids; Solanales; Solanaceae;
OC   Nicotianoideae; Nicotianeae; Nicotiana.
OX   NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT05685.1, ECO:0000313|Proteomes:UP000187609};
RN   [1] {ECO:0000313|EMBL:OIT05685.1, ECO:0000313|Proteomes:UP000187609}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC   TISSUE=Leaves {ECO:0000313|EMBL:OIT05685.1};
RA   Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K.,
RA   Ling Z., Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E.,
RA   Pandey P., Pandey S.P., Timmermann B., Baldwin I.T.;
RT   "The genome of Nicotiana attenuata.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Converts the prephenate produced from the shikimate-
CC       chorismate pathway into phenylalanine.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + L-arogenate = CO2 + H2O + L-phenylalanine;
CC         Xref=Rhea:RHEA:12536, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:58095, ChEBI:CHEBI:58180;
CC         EC=4.2.1.91; Evidence={ECO:0000256|RuleBase:RU363004};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-
CC       phenylalanine from L-arogenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OIT05685.1}.
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DR   EMBL; MJEQ01037184; OIT05685.1; -; Genomic_DNA.
DR   RefSeq; XP_019267725.1; XM_019412180.1.
DR   EnsemblPlants; OIT05685; OIT05685; A4A49_01653.
DR   GeneID; 109245005; -.
DR   Gramene; OIT05685; OIT05685; A4A49_01653.
DR   KEGG; nau:109245005; -.
DR   KO; K05359; -.
DR   OMA; ASNCARD; -.
DR   OrthoDB; 1090069at2759; -.
DR   UniPathway; UPA00121; UER00344.
DR   Proteomes; UP000187609; Chromosome 2.
DR   GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR   GO; GO:0047769; F:arogenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Chloroplast {ECO:0000256|RuleBase:RU363004};
KW   Complete proteome {ECO:0000313|Proteomes:UP000187609};
KW   Lyase {ECO:0000256|RuleBase:RU363004};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Plastid {ECO:0000256|RuleBase:RU363004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW   Transit peptide {ECO:0000256|RuleBase:RU363004}.
FT   DOMAIN      114    289       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      303    394       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   399 AA;  44190 MW;  0857E97B8B61DAF9 CRC64;
     MALKTVPIWA CGTNQQHCCT YPKSLKLGFP DYGSRLSGSN FLNFRPFRKW ECLVLLSERA
     ITPVEDEEPL TSPAGAEDTQ ITHSKRFHRD LQSLPKPLSA TGPSFGQGDG SKVRVAYQGI
     PGAYSEAAAL KAYPKCETVP CDQFEAAFKA VELWLVDKAV LPIENSVGGS IHRNYDLLLR
     HRLHIVGEVQ LVVNHCLLGL PGVRKEELKR VVSHPQALEQ CNITLNKLGV TRVNGDDTAS
     AAQIVASEGT RDTGAVASAR AAEIYGLSIL AERIQDDQDN ITRFLILARE PIIPGTDRPY
     KTSIVFTLEE GPGVLFKALA VFALREINLT KIESRPQKKR PLRVVDDSNK GSAKYFDYLF
     YIDFEASMAE PRAQYALGHL QEFARFIRVL GCYPMDTAL
//
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