ID A0A1J6IL89_NICAT Unreviewed; 624 AA.
AC A0A1J6IL89;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN Name=PUB14 {ECO:0000313|EMBL:OIT05909.1};
GN ORFNames=A4A49_39063 {ECO:0000313|EMBL:OIT05909.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT05909.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT05909.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT05909.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT05909.1}.
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DR EMBL; MJEQ01037184; OIT05909.1; -; Genomic_DNA.
DR RefSeq; XP_019225259.1; XM_019369714.1.
DR AlphaFoldDB; A0A1J6IL89; -.
DR STRING; 49451.A0A1J6IL89; -.
DR EnsemblPlants; OIT05909; OIT05909; A4A49_39063.
DR GeneID; 109206848; -.
DR Gramene; OIT05909; OIT05909; A4A49_39063.
DR KEGG; nau:109206848; -.
DR OMA; SKRMYSN; -.
DR OrthoDB; 2721872at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000187609; Chromosome 2.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd21037; MLKL_NTD; 1.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.20.930.20; Adaptor protein Cbl, N-terminal domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036537; Adaptor_Cbl_N_dom_sf.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF111; U-BOX DOMAIN-CONTAINING PROTEIN 14; 1.
DR Pfam; PF00514; Arm; 2.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 5.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 244..318
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 383..425
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 424..466
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 506..543
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 624 AA; 68065 MW; 71CCEEFA059E0C53 CRC64;
MDHEKDALIN ELTELIDTVS GLPECKNVSK RMYSNLVRRV KLLSPLVEEL KDSDVVEVGD
DVVHGLELLR IALNSALELL KSVNEGSKIF QALQMDTISL RFLNVTEQIE DALSHIPYNK
LDISEEVREQ IELVHAQFKR AKGKMESPDV QLVIDLAMAE REQDPDSMIF KRLSEKLHLR
TVNDLKKESL AIHDMVISSG GVPEECFETI AFLLRKLKDC AMTGNPEMDV LEGDKSMIKH
RSPVIPDDFR CPISLELMKD PVIVSTGQTY ERSCIQKWLD AGHKTCPKTQ QTLLHTALTP
NYVLKSLIAL WCENNGVELP KNQGNCRNKR SGAGGSDCDR AAIDALLQKL ANGNPEQQRA
AAGELRLLAK RNADNRVCIA EAGAIPLLVE LLSSSDSRTQ EHAVTALLNL SINESNKGTI
VNAGAIPDIV DVLRNGSMEA RENAAATLFS LSVVDENKVA IGAAGAIPAL IDLLCQGTPR
GKKDAATAIF NLSIYQGNKV RAVRAGIVPP LMRLLKDPGG GMMDEALAIL AILASHQEGK
AAIGQAEPIP ILVEVIRTGS PRNRENAAAV LWSLCTGDVQ NLKVARDLGV EEVLKELSEN
GTDRAKRKAG SVLELLQRVD AVDS
//
