ID A0A1J6ILB5_NICAT Unreviewed; 908 AA.
AC A0A1J6ILB5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Dna mismatch repair protein msh6 {ECO:0000313|EMBL:OIT05490.1};
GN Name=MSH6_3 {ECO:0000313|EMBL:OIT05490.1};
GN ORFNames=A4A49_11927 {ECO:0000313|EMBL:OIT05490.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT05490.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT05490.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT05490.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT05490.1}.
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DR EMBL; MJEQ01037184; OIT05490.1; -; Genomic_DNA.
DR RefSeq; XP_019266052.1; XM_019410507.1.
DR AlphaFoldDB; A0A1J6ILB5; -.
DR STRING; 49451.A0A1J6ILB5; -.
DR EnsemblPlants; OIT05490; OIT05490; A4A49_11927.
DR GeneID; 109243564; -.
DR Gramene; OIT05490; OIT05490; A4A49_11927.
DR KEGG; nau:109243564; -.
DR OMA; IHAIIND; -.
DR OrthoDB; 5490617at2759; -.
DR Proteomes; UP000187609; Chromosome 2.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR Gene3D; 3.30.1370.110; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR046893; MSSS.
DR InterPro; IPR005747; MutS2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002625; Smr_dom.
DR InterPro; IPR036063; Smr_dom_sf.
DR PANTHER; PTHR48378; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR48378:SF2; SMR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF20297; MSSS; 1.
DR Pfam; PF00488; MutS_V; 1.
DR Pfam; PF01713; Smr; 1.
DR PIRSF; PIRSF005814; MutS_YshD; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SMART; SM00463; SMR; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF160443; SMR domain-like; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
DR PROSITE; PS50828; SMR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609}.
FT DOMAIN 837..908
FT /note="Smr"
FT /evidence="ECO:0000259|PROSITE:PS50828"
FT COILED 199..230
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 622..670
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 908 AA; 100763 MW; 33B38AD5AF150AEE CRC64;
MNLFNCKFNN TLFTNHLPPR HTSLYNPRAT RFSVRFSSES THRDKLAESL QSETLKLLEW
PAVCRQLSAF TSTSMGFAAA QSALIPVGKT PEESGKLLSQ TSAAVAVPRP LDFSGIEDVS
PIVNASIAGG VLSIRELCSV KRTLGAARFL LQQLEEIASL SDFSGRYSPL KEILHNCDFL
VELEQKIEFC IDCSFSAILD RASEDLEIIR SERKRNMENL ESLLKQLSTQ VFQGGGFDRP
LVTKRRSRLC VAVRASHRSL LPNAVILDTS SSGSTYFMEP KEAVELNNME VKLSSSERIE
EQTILSLLTS EIAESNMKIK HLLDRILEID LAFARAAHAQ WIGGACPALS SRNCNNSQSE
LLSIDVEGIR HPLLLESSLR NLSTDVSPRS PVLDQGNGVM NFETKSRAHF PVPIDIKVGH
GTKVVVISGP NTGGKTASMK TLGLASMMLK AGMYLPAQNQ PRLPWFDLIL ADIGDQQSLE
QSLSTFSGHI SRLREILEVA SRESLVLIDE IGSGTDPSEG VALSESILQY LKDRVNLAVI
TTHYADLTRL KEKDNRFETA ATEFSLETLQ PTYRILWGSK GESNALNIAK SMGFDERIID
RAVLWVNKLT PDKQQEQKGL LYRSLIEERD RLESQAMEAA SLHSDIMKLY NEINKEAQDL
EGREAAIKAK ETHEIQQEVR TVKNEIHTIV EKFESQLRNA SADEINPLVK KAESAIASIV
EAHQPSKDFL FREIGQSRYT PQVGEQVYVK AFGNKLATVV EEPGDDDSIL VQYGKIRVRV
DKRSIRPIPP DASSSATVLK TQVQRIKSLR DLGSLAEAGK NQQDSYGPVL QTSKNTIDLR
GLRVEDASHQ LNMAIDSRAP NSVLFVIHGM GTGAVKESAH KLLRDHPRVV KFEQESPMNY
GCTVAYIK
//
