ID A0A1J6IM05_NICAT Unreviewed; 358 AA.
AC A0A1J6IM05;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Auxin efflux carrier component {ECO:0000256|RuleBase:RU362108};
GN Name=PIN8 {ECO:0000313|EMBL:OIT05878.1};
GN ORFNames=A4A49_13310 {ECO:0000313|EMBL:OIT05878.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT05878.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT05878.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT05878.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May act as a component of the auxin efflux carrier.
CC {ECO:0000256|RuleBase:RU362108}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362108}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362108}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC {ECO:0000256|ARBA:ARBA00009177, ECO:0000256|RuleBase:RU362108}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362108}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT05878.1}.
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DR EMBL; MJEQ01037184; OIT05878.1; -; Genomic_DNA.
DR RefSeq; XP_019242742.1; XM_019387197.1.
DR AlphaFoldDB; A0A1J6IM05; -.
DR STRING; 49451.A0A1J6IM05; -.
DR EnsemblPlants; OIT05878; OIT05878; A4A49_13310.
DR GeneID; 109222906; -.
DR Gramene; OIT05878; OIT05878; A4A49_13310.
DR KEGG; nau:109222906; -.
DR OMA; WHIRLPL; -.
DR OrthoDB; 405852at2759; -.
DR Proteomes; UP000187609; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0060918; P:auxin transport; IEA:UniProt.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-UniRule.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR014024; Auxin_eff_plant.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR NCBIfam; TIGR00946; 2a69; 1.
DR PANTHER; PTHR31752; AUXIN EFFLUX CARRIER COMPONENT 1B-RELATED; 1.
DR PANTHER; PTHR31752:SF40; AUXIN EFFLUX CARRIER COMPONENT 8; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294,
KW ECO:0000256|RuleBase:RU362108};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362108};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362108};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362108}; Transport {ECO:0000256|RuleBase:RU362108}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 251..270
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 276..297
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 329..355
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
SQ SEQUENCE 358 AA; 39359 MW; 24E24C2B069CD41E CRC64;
MISLRDVYHV VAATIPLYVV MILAYISVRW WKLFSPEQCS GINKFVAKFS IPLLSFQVIS
ESNLYKVNLK LLLADFIQKF VAVFLLAVFA KLKPKGKLTW IITGLSVSTL PNTLILGIPL
VKAIFGDAAA ELLVQIIVLQ SLIWYNLLLF LFELNATKES YMPSPSEVAV ELEVPEESEL
EEDREEEAKA ICPRKTKIML ILLTVGRKLI INPNTHATLA GIIWSSIHFR WGINLPTIVG
RSISILSDGG LGMAMFSIGV FMASQASIIA CGTRKAILAM ALKFVLGPVL MAISSIAVGL
RGKLLKLAIV QAALPQGIVP FVFAKEYNIH PTILSTGVIF GMLIAIPIAL AYYFLLEI
//
