ID A0A1J6ITD8_NICAT Unreviewed; 376 AA.
AC A0A1J6ITD8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=ornithine carbamoyltransferase {ECO:0000256|ARBA:ARBA00013007};
DE EC=2.1.3.3 {ECO:0000256|ARBA:ARBA00013007};
GN Name=OTC {ECO:0000313|EMBL:OIT00983.1};
GN ORFNames=A4A49_12784 {ECO:0000313|EMBL:OIT00983.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT00983.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT00983.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT00983.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=carbamoyl phosphate + L-ornithine = H(+) + L-citrulline +
CC phosphate; Xref=Rhea:RHEA:19513, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:46911, ChEBI:CHEBI:57743,
CC ChEBI:CHEBI:58228; EC=2.1.3.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001065};
CC -!- SIMILARITY: Belongs to the aspartate/ornithine carbamoyltransferase
CC superfamily. OTCase family. {ECO:0000256|ARBA:ARBA00007805}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT00983.1}.
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DR EMBL; MJEQ01037189; OIT00983.1; -; Genomic_DNA.
DR RefSeq; XP_019250325.1; XM_019394780.1.
DR AlphaFoldDB; A0A1J6ITD8; -.
DR STRING; 49451.A0A1J6ITD8; -.
DR EnsemblPlants; OIT00983; OIT00983; A4A49_12784.
DR GeneID; 109229362; -.
DR Gramene; OIT00983; OIT00983; A4A49_12784.
DR KEGG; nau:109229362; -.
DR OMA; IFYPKYQ; -.
DR OrthoDB; 2782890at2759; -.
DR Proteomes; UP000187609; Chromosome 7.
DR GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR GO; GO:0004585; F:ornithine carbamoyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1370; Aspartate/ornithine carbamoyltransferase; 2.
DR HAMAP; MF_01109; OTCase; 1.
DR InterPro; IPR006132; Asp/Orn_carbamoyltranf_P-bd.
DR InterPro; IPR006130; Asp/Orn_carbamoylTrfase.
DR InterPro; IPR036901; Asp/Orn_carbamoylTrfase_sf.
DR InterPro; IPR006131; Asp_carbamoyltransf_Asp/Orn-bd.
DR InterPro; IPR002292; Orn/put_carbamltrans.
DR InterPro; IPR024904; OTCase_ArgI.
DR NCBIfam; TIGR00658; orni_carb_tr; 1.
DR PANTHER; PTHR45753; ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45753:SF3; ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL; 1.
DR Pfam; PF00185; OTCace; 1.
DR Pfam; PF02729; OTCace_N; 1.
DR PRINTS; PR00100; AOTCASE.
DR PRINTS; PR00102; OTCASE.
DR SUPFAM; SSF53671; Aspartate/ornithine carbamoyltransferase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003634}.
FT DOMAIN 74..215
FT /note="Aspartate/ornithine carbamoyltransferase carbamoyl-P
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02729"
FT DOMAIN 221..372
FT /note="Aspartate/ornithine carbamoyltransferase Asp/Orn-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF00185"
SQ SEQUENCE 376 AA; 41454 MW; 021020E39689CFC9 CRC64;
MAAIFSHLSS LRSSDAPSFS SLSHYGIQLS RPSGAFVPSP VTFPAIRRRI SCQTSSPASS
PSSSVNGNAN ANQKDFLHIS DFDKSTILNI LDRAKEVKAL IKSGEKTYLP FQGKTMAMIF
AKPSMRTRVS FETGFYLLGG HAIYLGPNDI QMGKREETRD IARVLSRYND IIMARVFAHQ
DILDLAKYAT VPVINGLTDY NHPCQIMADA LTIIEHVGQL EGTKVVYIGD GNNIVHSWLL
LASVIPFHFV CACPKGFEPD EETVKKAQQS GVSKIEITND PKEAVRGADV VYSDVWASMG
QKEEAAQRRQ VFHGFQVNEE IMKLAGHKAY FMHCLPAERG VEVTDGVIEA PNSIVFPQAE
NRMHAQNAIM LHVMGL
//
