ID A0A1J6IUY4_NICAT Unreviewed; 896 AA.
AC A0A1J6IUY4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Formin-like protein {ECO:0000256|RuleBase:RU361260};
GN Name=FH6_0 {ECO:0000313|EMBL:OIT08538.1};
GN ORFNames=A4A49_01788 {ECO:0000313|EMBL:OIT08538.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT08538.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT08538.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT08538.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000256|ARBA:ARBA00025793}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT08538.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MJEQ01037183; OIT08538.1; -; Genomic_DNA.
DR RefSeq; XP_019251367.1; XM_019395822.1.
DR AlphaFoldDB; A0A1J6IUY4; -.
DR STRING; 49451.A0A1J6IUY4; -.
DR EnsemblPlants; OIT08538; OIT08538; A4A49_01788.
DR GeneID; 109230306; -.
DR Gramene; OIT08538; OIT08538; A4A49_01788.
DR KEGG; nau:109230306; -.
DR OMA; NRYHARQ; -.
DR OrthoDB; 623207at2759; -.
DR Proteomes; UP000187609; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213:SF391; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..896
FT /note="Formin-like protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013380757"
FT TRANSMEM 116..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 447..871
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 149..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 614..641
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 226..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..314
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..378
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..464
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 896 AA; 99382 MW; DC9C508FFAD83309 CRC64;
MKVHFLSNFL ILLSFTAQLV IRGADTQIQD FNGKEKTRRI LHQPLFPVTS SPPPNSELSP
PVEPIFPSPD QPFFPEVPTV PTSDQTQQQS PPIQANYGTP ISHPIAPQPQ NPTKKLAIAI
SVGIVTLGML SALAFYLYKH SVKQPDETQK LVGNNNSQRN NQESRMPPSN FLYIGTVEPS
ANNTSVNQSN VANSSPYRKL TSVKISDRYR PSPELHPLPP LRNSIINSPP RMSLSDEENH
NTTFYNPCST SINKQLRVEN HVNKSIPHSK RTSPRLSLSG SSPDIKRAII PSIKQNSAPP
PPPPPPPQPH HLTEFPEQPP LQHKKRVLSY LPHRATFSSP PPPPDMSRLK SISNQSQQTS
KVPAPPPPPP PPPPLLSTPR KLGSGVSSKA TNSMEPPLRG GLHRSDTSTS SPQVVKTPSS
SPTPKSTPES EKKRTLEEQN GEARHDTDTT DESKPKLKPL HWDKVRATSE RATVWDQLKS
SSFQLNEDMM ESLFGCNNSA NSAPTVTTKK SVRPPVEKEN SVLDPKKSQN IAIMLRALNV
TKDEVSEALL DGNAEGLGPE LLETLVKMAP TKEEEIKLRD YNGDTSKLGS AERFLKAILD
IPFAFKRVEA MLYRANFDAE VKDLRKSFQT LEEASRELKN SRLFFKLLEA VLRAGNRMNV
GTNRGDARAF KLETLLKLID IKGTDGKTTL LHFVVQEIIR SEGLSSDTRD DNLPNISNIK
FKEEEFKKQG LQVVAGLSRE LGNVKKAAGM DSDVLSGYVS KLEAGLVKAR SILQYEKKGT
EGNFFESMKV FLKEAEDGIV RIKAEERKAL SMVKEVTEYF HGDAAKEEAH PLRIFVIVRD
FLSILDSVCK DVGMMQDRTM VGAARSFRIA ATTSLPVLNR YNASQDRCWD DNSLSP
//
