ID A0A1J6IZI0_NICAT Unreviewed; 610 AA.
AC A0A1J6IZI0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glutamate receptor 2.6 {ECO:0000313|EMBL:OIT04171.1};
GN Name=GLR2.6 {ECO:0000313|EMBL:OIT04171.1};
GN ORFNames=A4A49_23301 {ECO:0000313|EMBL:OIT04171.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT04171.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT04171.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT04171.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT04171.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MJEQ01037186; OIT04171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J6IZI0; -.
DR EnsemblPlants; OIT04171; OIT04171; A4A49_23301.
DR Gramene; OIT04171; OIT04171; A4A49_23301.
DR OMA; ATYCKGY; -.
DR Proteomes; UP000187609; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966:SF401; IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:OIT04171.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..610
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012362789"
FT TRANSMEM 562..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..382
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
FT DOMAIN 465..543
FT /note="Solute-binding protein family 3/N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00497"
SQ SEQUENCE 610 AA; 68048 MW; 7727BE0B297AB0B1 CRC64;
MRTATTHVFS LLVYFLLIYQ MANNKNGVNG SVNDDCNIIW RIGAIIDPIS RLGKEQKVAI
EMAVHEFNGQ NSKCSELVFD FAYYSHGSSS PAASIATYLV NKKQVHAILE PLTQQEAVLF
SEFDESYKGI PIISLSPSAT YSPQLVLPQD PPSSLVQMSD DVKSQMQCIA ALIGHFKWRK
VIALYEIINS FSNMDSGLIT HLSDSLKVVD STVEYHLAFP PLLSLSNSKS FIKEELEKLK
TKNMKVFVVV QCSLDFGLVL FEMATEMGMM GKDYVWIISD NMASFLDSVE PSVLLNMQGV
IGFKSNVNEK RNPSPSFYAL KAYDATWAIA KAMKNLTKVK NSSSELVKTI LLSDFEGLSG
KVSFKNGVIF QKPIFKIINV IGKSYREVSF WSPEFGFVND LVEYNGVKLK IGNGLESILW
PGGKQTVPKG WSIGGLEKPL KIGVPAKGAF NQFVTVNFNQ ERNETIIGGF SVHVFEAVVR
QLPYYLPYVL VPFYGTYDEM VVGVSNKNLD AAVGDTEIMA DRYEYAEFSQ PYIDSGLVMI
VTERPILKRP PFIVVKAFKL KLWILLAVMS MSTGVVIWLN EYANNNPDFS GSFPQLIGSM
LWFSVTVLSF
//
