ID A0A1J6JA88_NICAT Unreviewed; 449 AA.
AC A0A1J6JA88;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Enhancer of polycomb-like protein {ECO:0000256|RuleBase:RU361124};
GN ORFNames=A4A49_31007 {ECO:0000313|EMBL:OIT06663.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT06663.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT06663.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT06663.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC is involved in transcriptional activation of selected genes principally
CC by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. Involved in gene silencing by neighboring
CC heterochromatin, blockage of the silencing spreading along the
CC chromosome, and required for cell cycle progression through G2/M.
CC {ECO:0000256|ARBA:ARBA00025513}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU361124}.
CC -!- SIMILARITY: Belongs to the enhancer of polycomb family.
CC {ECO:0000256|ARBA:ARBA00008035, ECO:0000256|RuleBase:RU361124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT06663.1}.
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DR EMBL; MJEQ01037184; OIT06663.1; -; Genomic_DNA.
DR RefSeq; XP_019232297.1; XM_019376752.1.
DR AlphaFoldDB; A0A1J6JA88; -.
DR STRING; 49451.A0A1J6JA88; -.
DR EnsemblPlants; OIT06663; OIT06663; A4A49_31007.
DR GeneID; 109213004; -.
DR Gramene; OIT06663; OIT06663; A4A49_31007.
DR KEGG; nau:109213004; -.
DR OMA; PIKYGVF; -.
DR OrthoDB; 1343374at2759; -.
DR Proteomes; UP000187609; Chromosome 2.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR InterPro; IPR024943; Enhancer_polycomb.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR PANTHER; PTHR14898; ENHANCER OF POLYCOMB; 1.
DR PANTHER; PTHR14898:SF0; ENHANCER OF POLYCOMB-LIKE PROTEIN; 1.
DR Pfam; PF10513; EPL1; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU361124};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU361124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU361124}.
FT DOMAIN 39..137
FT /note="Enhancer of polycomb-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10513"
FT COILED 245..285
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 449 AA; 51565 MW; ECFCDF45D3CF10D6 CRC64;
MSRLSFRPRP LDIHKKLPIL KSVKDFEDDD TPSNTRNHII RLAAEAADVE VQQTSSKKLV
PEIPIPEYVV VDTYERDYSR TFAQPTSYIH ARGARAEIGE FVEYDLDNED EDWLQDINRE
RKALAAEKLE TILHKLEVLD HKARERAGVI TPTLGSPIPV ILSFDAAVEA LQSLTIKYGV
FQSVYTYWKD KRERWQKPIL RRLQPPPPVS DTNPYNVFRP REKAHRLHTR RMQRRENNVQ
SFEKLRQVRR NLDQAKTILE ALIKREEKKR EVVESEVSLQ RLQMKHKNEI ELFEDTLALP
GFPSFPTKVG SSEEEYMDSD DAAISRPHAQ SAVSPNLFSD SKPVMASAGS MRRERELKRR
YVPYGWLHKL DPTEPLLLFT KPLDPENMAA AGILPPMGNG LAACTFNSRG RIGRGGRIVF
DRWNPLMHTP IDCGDALYVP PKGRHSAHP
//
