ID A0A1J6JJP2_NICAT Unreviewed; 253 AA.
AC A0A1J6JJP2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=NAD(P)H dehydrogenase (quinone) {ECO:0000256|ARBA:ARBA00012648};
DE EC=1.6.5.2 {ECO:0000256|ARBA:ARBA00012648};
GN ORFNames=A4A49_01421 {ECO:0000313|EMBL:OIT07153.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT07153.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT07153.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT07153.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinone + H(+) + NADH = a quinol + NAD(+);
CC Xref=Rhea:RHEA:46160, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124; EC=1.6.5.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000882};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinone + H(+) + NADPH = a quinol + NADP(+);
CC Xref=Rhea:RHEA:46164, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:132124; EC=1.6.5.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000139};
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- SIMILARITY: Belongs to the WrbA family.
CC {ECO:0000256|ARBA:ARBA00006961}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT07153.1}.
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DR EMBL; MJEQ01037183; OIT07153.1; -; Genomic_DNA.
DR RefSeq; XP_019250292.1; XM_019394747.1.
DR AlphaFoldDB; A0A1J6JJP2; -.
DR STRING; 49451.A0A1J6JJP2; -.
DR EnsemblPlants; OIT07153; OIT07153; A4A49_01421.
DR GeneID; 109229313; -.
DR Gramene; OIT07153; OIT07153; A4A49_01421.
DR KEGG; nau:109229313; -.
DR OMA; EQMKVPK; -.
DR OrthoDB; 343642at2759; -.
DR Proteomes; UP000187609; Chromosome 1.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.360; -; 1.
DR InterPro; IPR008254; Flavodoxin/NO_synth.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR010089; Flavoprotein_WrbA-like.
DR NCBIfam; TIGR01755; flav_wrbA; 1.
DR PANTHER; PTHR30546; FLAVODOXIN-RELATED PROTEIN WRBA-RELATED; 1.
DR PANTHER; PTHR30546:SF59; NAD(P)H DEHYDROGENASE (QUINONE); 1.
DR Pfam; PF00258; Flavodoxin_1; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
DR PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000187609}.
FT DOMAIN 45..233
FT /note="Flavodoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS50902"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 253 AA; 27409 MW; C4BF0B235D0CE198 CRC64;
MGKGGGCMPS KKKFPINESA ERPVSQTEGT DVTGSETEGS KKLRIFIVFY SMYGHIESLA
KKMKKGVDGI EGVEGVLYRV PETLTIDVLE KMKVPQKDDE IPVISVDELV EADGFLFGFP
TRYGCMAAQM KAFFDSTGQL WRAQKLAGVP AGFFVSTGTQ GGGQETTAWT AITQLAHHGM
VYVPIGYTFG AGMFRMDSIR GGSPYGAGTF SGDGSREPSE QELALAEHQG KYMAMTVRRM
AQHHSLPPDN PSC
//
