ID A0A1J6JY65_NICAT Unreviewed; 214 AA.
AC A0A1J6JY65;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Werner syndrome-like exonuclease {ECO:0000313|EMBL:OIT22709.1};
GN Name=WEX_4 {ECO:0000313|EMBL:OIT22709.1};
GN ORFNames=A4A49_37208 {ECO:0000313|EMBL:OIT22709.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT22709.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT22709.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT22709.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT22709.1}.
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DR EMBL; MJEQ01003544; OIT22709.1; -; Genomic_DNA.
DR RefSeq; XP_019237019.1; XM_019381474.1.
DR AlphaFoldDB; A0A1J6JY65; -.
DR STRING; 49451.A0A1J6JY65; -.
DR EnsemblPlants; OIT22709; OIT22709; A4A49_37208.
DR GeneID; 109217242; -.
DR Gramene; OIT22709; OIT22709; A4A49_37208.
DR KEGG; nau:109217242; -.
DR OMA; MSRWDAY; -.
DR OrthoDB; 1218145at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06141; WRN_exo; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR13620; 3-5 EXONUCLEASE; 1.
DR PANTHER; PTHR13620:SF104; EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:OIT22709.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609}.
FT DOMAIN 36..212
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
SQ SEQUENCE 214 AA; 24480 MW; 0C8CA75A782C02AB CRC64;
MTTFRIVDNE EQDNRYDLFD VYFHSDTIKT TVTSDPEIVT QWISETESSL HDRRHLIVGL
DVEWRPSFHR NQQFKVATLQ LCVDRRCLIF QLLYCSSIPD SLVSFLSNGD YTFVGVGVEN
DVEKLVEDHD LSVSNMVDLR ALAADAYEMS NLKTAGLKEL CNVVLGREIE KPRHITMGRW
DSEWLSLDQI KYACVDAFVS FEIAKHLNVA AAAP
//
