ID A0A1J6KC67_NICAT Unreviewed; 649 AA.
AC A0A1J6KC67;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Cationic amino acid transporter 2, vacuolar {ECO:0000313|EMBL:OIT27658.1};
GN Name=CAT2_0 {ECO:0000313|EMBL:OIT27658.1};
GN ORFNames=A4A49_27002 {ECO:0000313|EMBL:OIT27658.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT27658.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT27658.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT27658.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
CC {ECO:0000256|ARBA:ARBA00008572}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT27658.1}.
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DR EMBL; MJEQ01002324; OIT27658.1; -; Genomic_DNA.
DR RefSeq; XP_019233025.1; XM_019377480.1.
DR AlphaFoldDB; A0A1J6KC67; -.
DR EnsemblPlants; OIT27658; OIT27658; A4A49_27002.
DR GeneID; 109213658; -.
DR Gramene; OIT27658; OIT27658; A4A49_27002.
DR KEGG; nau:109213658; -.
DR OMA; LMFGWAP; -.
DR OrthoDB; 1421713at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 2.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR029485; CAT_C.
DR PANTHER; PTHR43243; INNER MEMBRANE TRANSPORTER YGJI-RELATED; 1.
DR PANTHER; PTHR43243:SF4; LD37241P; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF13906; AA_permease_C; 1.
DR PIRSF; PIRSF006060; AA_transporter; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 573..623
FT /note="Cationic amino acid transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13906"
SQ SEQUENCE 649 AA; 68084 MW; 9771111398C805A0 CRC64;
MGFVGDTEKI DRGSGSGDKG GCFFGGMKSL VRRKQVDSAN SKSGSSHQLA KALTVPHLIA
IGVGSTIGAG VYILVGTVAR EHSGPALTIS FLIAGIAAAL SAFCYAELAS RCPSAGSAYH
YSYICVGEGV AWLIGWAVVL EYTIGGSAVA RGISPNLAML FGGPDSLPTF LARHTIPGLN
VTVDPCAAIL VFVVTGLLCV GIKESTMVQG FVTAVNICAM FFVIVAGGYL GFKTGWPGYE
LPVGYFPFGA DGMLAGASTV FFAYIGFDSV ASTAEEVKNP QRDLPMGIGF ALSICCTLYM
LVSAVIVGLV PYYAMDPDTP ISSAFASHGI NWAAYIITVG ACTSLCSTLM GSILPQPRIL
MAMARDGLLP SFFSDVNKRT QVPVKGTVAT GLLSGILAFF MDVEQLSGMV SVGTLLAFTM
VAISVLILRY VPPDEVPLPS SFQEAIDSVS LRHSGCNSGS DIDVETTKIP AVTSGDSTPL
LVEISVGHPL VEKAAAKLNY LVRQRRKVAG WTIMFICIGV FILTSAASIV SLPNPARYTL
CGIGGFLLLS GLIVLTCIDQ DDGRHSFGHT GGFTCPFVPL LPIACILINV YLLINLGGAT
WARVSIWLLL GACIYALYGR THSSLKNAVY VPATHVDEIY QTSANSLAC
//
