ID A0A1J6KTG6_NICAT Unreviewed; 319 AA.
AC A0A1J6KTG6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=choline-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00026101};
DE EC=2.7.7.15 {ECO:0000256|ARBA:ARBA00026101};
GN Name=CCT1_1 {ECO:0000313|EMBL:OIT28064.1};
GN ORFNames=A4A49_28048 {ECO:0000313|EMBL:OIT28064.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT28064.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT28064.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT28064.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT28064.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MJEQ01002183; OIT28064.1; -; Genomic_DNA.
DR RefSeq; XP_019232415.1; XM_019376870.1.
DR AlphaFoldDB; A0A1J6KTG6; -.
DR STRING; 49451.A0A1J6KTG6; -.
DR EnsemblPlants; OIT28064; OIT28064; A4A49_28048.
DR GeneID; 109213109; -.
DR Gramene; OIT28064; OIT28064; A4A49_28048.
DR OMA; MHHNEWV; -.
DR OrthoDB; 5474784at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0004105; F:choline-phosphate cytidylyltransferase activity; IEA:InterPro.
DR CDD; cd02174; CCT; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR045049; Pcy1-like.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR PANTHER; PTHR10739:SF56; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE 2; 1.
DR PANTHER; PTHR10739; CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Nucleotidyltransferase {ECO:0000313|EMBL:OIT28064.1};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Transferase {ECO:0000313|EMBL:OIT28064.1}.
FT DOMAIN 31..160
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 192..219
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 279..304
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 37289 MW; 90EE94F5CD15366E CRC64;
MGETGVATAE HNNQHHCVND LPPSDRPVRV YADGIYDLFH FGHARSLEQA KKSFPNTYLL
VGCCSDEMTH KYKGRTVMTE EERYESLRHC KWVDEVIPDA PWVISQEFLD KHHIDYVAHD
ALPYADASGA GKDVYEFVKA VGRFKETKRT DGISTSDVIM RIIKDYNKYV MRNLDRGYSR
KELGVSYVKE KRLRVNMRLM KLQEKVKEHQ EKVGEKIQTV AKTAGMHHNE WIENADRWVA
GFLQMFEESC HKMGTAIRDR IQERSRGQKS RDLLENGNTI DTDEEEDDEY YYVEEEEEEY
FDNEEQHIED KKNSSSSTE
//
